Cortenema (Hydrocortisone) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Cortenema

Ulcerative Colitis »

What is Ulcerative Colitis?

Ulcerative colitis is a chronic inflammation of the large intestine (colon). The colon is the part of the digestive system where waste material is stored. The rectum is the end of the colon adjacent to the anus. In patients with ulcerative colitis, ulcers and inflammation of the inner lining of the colon lead to symptoms of abdominal pain, diarrhea, and rectal bleeding.

Ulcerative colitis is closely related to another condition of inflammation of the intestines called Crohn's disease. Together, they are frequently referred to as inflammatory bowel disease (IBD). Ulcerative colitis and Crohn's diseases are chronic conditions that can last years to decades. They affect approximately 500,000 to 2 million people In the United States. Men and women are affected equally. They most commonly begin during adolescence and early adulthood, but they also can begin during childhood and later in life.

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Cortenema

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CORTENEMA®
(hydrocortisone retention enema) 100mg/60mL

DISPOSABLE UNIT FOR RECTAL USE ONLY

DRUG DESCRIPTION

Hydrocortisone is a white to practically white, odorless, crystalline powder, very slightly soluble in water. It has the chemical name Pregn-4-ene-3,20-dione,11,17,21- trihydroxy-,(11β) and the following structural formula:

CORTENEMA (hydrocortisone) structural formula illustration

CORTENEMA* is a convenient disposable single-dose hydrocortisone enema designed for ease of self-administration.

Each disposable unit (60 mL) contains: Hydrocortisone, 100 mg in an aqueous solution containing carbomer 934P, polysorbate 80, purified water, sodium hydroxide and methylparaben, 0.18% as a preservative.

What are the possible side effects of hydrocortisone rectal foam or enema (Colocort, Cortenema, Cortifoam)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

feeling short of breath, even with mild exertion;
swelling of your ankles or feet;
muscle weakness;
rapid weight gain, especially in your face and midsection;
severe rectal pain or burning;

Read All Potential Side Effects and See Pictures of Cortenema »

What are the precautions when taking hydrocortisone (Cortenema)?

Before using hydrocortisone, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (such as prednisone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: other stomach/intestinal problems (such as ulcers, blockage, bleeding, infection, recent surgery), infections (such as tuberculosis, fungal infections), certain eye conditions (cataracts, glaucoma, herpes infection of the eye), heart problems (such as congestive heart failure, recent heart attack), high blood pressure, liver disease, kidney disease, thyroid problems...

Read All Potential Precautions of Cortenema »

Last reviewed on RxList: 3/12/2008
This monograph has been modified to include the generic and brand name in many instances.