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Cortenema Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Cortenema (hydrocortisone) rectal is used to treat hemorrhoids and itching or swelling of the rectal area caused by hemorrhoids or other inflammatory conditions of the rectum or anus. It is also used together with other medications to treat ulcerative colitis, proctitis, and other inflammatory conditions of the lower intestines and rectal area. It is a steroid. This medication is available in generic form. Common side effects include pain or burning in the rectum, dizziness, menstrual period changes, trouble sleeping, unusual weight gain, increased sweating, acne, or unusual hair growth.
The usual course of therapy is one Cortenema nightly for 21 days, or until the patient comes into remission. Before using Cortenema rectal, tell your doctor if you use insulin or oral diabetes medications. Other drugs may interact with Cortenema. Tell your doctor all prescription and over-the-counter medications you use. During pregnancy, Cortenema should be used only when prescribed and not for prolonged periods. Other forms of hydrocortisone (given by mouth or by injection) may harm a fetus. Infants born to mothers who have been using this medication may have low levels of the natural corticosteroid hormone in their bodies and may need more monitoring. Tell your doctor if you notice symptoms such as vomiting, severe diarrhea, or weakness in your newborn. It is unknown if this drug passes into breast milk. It is unlikely to harm a nursing infant. Consult your doctor before breast-feeding.
Our Cortenema (hydrocortisone) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Cortenema in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- feeling short of breath, even with mild exertion;
- swelling of your ankles or feet;
- muscle weakness;
- rapid weight gain, especially in your face and midsection;
- severe rectal pain or burning;
- bleeding from your rectum;
- severe stomach pain;
- sudden and severe headache or pain behind your eyes; or
- seizure (convulsions).
Less serious side effects may include:
- mild rectal pain or burning;
- changes in your menstrual periods;
- increased sweating; or
- increased facial or body hair growth.
Read the entire detailed patient monograph for Cortenema (Hydrocortisone) »
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Cortenema Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: persistent headache, swelling ankles/feet, increased thirst/urination, vision problems, puffy face, thinning skin, unusual skin growths, slow wound healing, persistent rectal bleeding, unusual bruising/bleeding, black/tarry stools, vomit that looks like coffee grounds, severe stomach/abdominal pain, severe heartburn, bone pain, easily broken bones, mental/mood changes (such as depression, mood swings, agitation), muscle weakness/pain, irregular heartbeat, signs of infection (such as fever, persistent sore throat, painful urination, worsening redness/irritation near the anus), seizures.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Cortenema (Hydrocortisone)»
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Cortenema FDA Prescribing Information: Side Effects
Local pain or burning, and rectal bleeding attributed to CORTENEMA (hydrocortisone) * have been reported rarely. Apparent exacerbations or sensitivity reactions also occur rarely. The following adverse reactions should be kept in mind whenever corticosteroids are given by rectal administration.
Fluid and Electrolyte Disturbances: Sodium retention; fluid retention; congestive heart failure in susceptible patients; potassium loss; hypokalemic alkalosis; hypertension. Musculoskeletal: Muscle weakness; steroid myopathy; loss of muscle mass; osteoporosis; vertebral compression fractures; asceptic necrosis of femoral and humeral heads; pathologic fracture of long bones. Gastrointestinal: Peptic ulcer with possible perforation and hemorrhage; pancreatitis; abdominal distention; ulcerative esophagitis. Dermatologic: impaired wound healing; thin fragile skin; petechiae and ecchymoses; facial erythema; increased sweating; may suppress reactions to skin tests. Neurological: Convulsions; increased intracranial pressure with papilledema (pseudo-tumor cerebri) usually after treatment; vertigo; headache. Endocrine: Menstrual irregularities; development of Cushingoid state; suppression of growth in pediatric patients; secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness, decreased carbohydrate tolerance; manifestations of latent diabetes requirements for insulin or oral hypoglycemic agents in diabetics. Opthalmic: Posterior subcapsular cataracts; increased intraocular pressure; glaucoma; exophthalmos. Metabolic: Negative nitrogen balance due to protein catabolism.
Read the entire FDA prescribing information for Cortenema (Hydrocortisone) »
Additional Cortenema Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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