Recommended Topic Related To:

Cortisporin Ointment

"Scientists at the National Institutes of Health report they have discovered in mouse studies that a small molecule released in the spinal cord triggers a process that is later experienced in the brain as the sensation of itch.

The small"...

Cortisporin Ointment

CORTISPORIN® Ointment
(neomycin and polymyxin B sulfates, bacitracin zinc, and hydrocortisone) Ointment, USP

DRUG DESCRIPTION

CORTISPORIN Ointment (neomycin and polymyxin b sulfates, bacitracin zinc, and hydrocortisone) (neomycin and polymyxin B sulfates, bacitracin zinc, and hydrocortisone ointment, USP) is a topical antibacterial ointment. Each gram contains: neomycin sulfate equivalent to 3.5 mg neomycin base, polymyxin B sulfate equivalent to 5,000 polymyxin B units, bacitracin zinc equivalent to 400 bacitracin units, hydrocortisone 10 mg (1%), and white petrolatum, qs.

Neomycin sulfate is the sulfate salt of neomycin B and C, which are produced by the growth of Streptomyces fradiae Waksman (Fam. Streptomycetaceae). It has a potency equivalent of not less than 600 g of neomycin standard per mg, calculated on an anhydrous basis. The structural formulae are:

Neomycin sulfate structural formula illustration

Polymyxin B sulfate is the sulfate salt of polymyxin B1 and B2, which are produced by the growth of Bacillus polymyxa (Prazmowski) Migula (Fam. Bacillaceae). It has a potency of not less than 6,000 polymyxin B units per mg, calculated on an anhydrous basis. The structural formulae are:

Polymyxin B sulfate structural formula illustration

Bacitracin zinc is the zinc salt of bacitracin, a mixture of related cyclic polypeptides (mainly bacitracin A) produced by the growth of an organism of the licheniformis group of Bacillus subtilis (Fam. Bacillaceae). It has a potency of not less than 40 bacitracin units per mg. The structural formula is:

Bacitracin zinc structural formula illustration

Hydrocortisone, 11β,17,21-trihydroxypregn-4-ene-3, 20-dione, is an anti-inflammatory hormone. Its structural formula is:

Hydrocortisone structural formula illustration

What are the precautions when taking neomycin and polymyxin b sulfates, bacitracin zinc, and hydrocortisone (Cortisporin Ointment)?

Before using this product, tell your doctor or pharmacist if you are allergic to neomycin, bacitracin, polymyxin, or hydrocortisone; or to aminoglycoside antibiotics (e.g., gentamicin, tobramycin); or to other corticosteroids (e.g., dexamethasone, prednisone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used to treat an infection in the outer ear canal if the eardrum is torn (perforated).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, a weakened immune system.

Children may be more sensitive to the effects of too much...

Read All Potential Precautions of Cortisporin Ointment »

Last reviewed on RxList: 4/29/2008
This monograph has been modified to include the generic and brand name in many instances.

A A A

Cortisporin Ointment - User Reviews

Cortisporin Ointment User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Cortisporin Ointment sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Women's Health

Find out what women really need.