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Cortisporin Ointment Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Cortisporin Ointment (neomycin and polymyxin B sulfates, bacitracin zinc, and hydrocortisone) is a topical (for the skin) combination of antibiotics and a corticosteroid used to treat bacterial skin infections. It will not work for other types of skin infections (e.g., infections caused by fungi, viruses). Common side effects include burning, redness, irritation, or dryness of the skin.
Apply a thin film dose of Cortisporin Ointment 2 to 4 times daily to the affected area. Therapy with Cortisporin Ointment should be limited to 7 days. Cortisporin Ointment may interact with antibiotics or oral corticosteroids. Tell your doctor all medications and supplements you use. During pregnancy, Cortisporin Ointment should be used only if prescribed. It is unknown if this medication passes into breast milk. Consult your doctor before breastfeeding.
Our Cortisporin Ointment (neomycin and polymyxin B sulfates, bacitracin zinc, and hydrocortisone) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Cortisporin Ointment Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: stretch marks, skin thinning/discoloration, acne, extreme/unwanted hair growth, "hair bumps" (folliculitis).
Rarely, use of this medication for prolonged or repeated periods may result in other types of skin infections (e.g., fungal or other bacterial infections). Contact your doctor if you notice any unusual skin symptoms or if your condition does not improve.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Cortisporin Ointment (Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Cortisporin Ointment FDA Prescribing Information: Side Effects
Neomycin occasionally causes skin sensitization. Ototoxicity and nephrotoxicity have also been reported. (See WARNINGS.) Adverse reactions have occurred with topical use of antibiotic combinations including neomycin, bacitracin, and polymyxin B. Exact incidence figures are not available since no denominator of treated patients is available. The reaction occurring most often is allergic sensitization. In one clinical study, using a 20% neomycin patch, neomycin-induced allergic skin reactions occurred in two of 2,175 (0.09%) individuals in the general population.1 In another study, the incidence was found to be approximately 1%.2
The following local adverse reactions have been reported with topical corticosteroids, especially under occlusive dressings: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria. When steroid preparations are used for long periods of time in intertriginous areas or over extensive body areas, with or without occlusive non-permeable dressings, striae may occur; also there exists the possibility of systemic side effects when steroid preparations are used over large areas or for a long period of time.
Read the entire FDA prescribing information for Cortisporin Ointment (Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone)
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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