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Naturally occurring glucocorticoids (hydrocor-tisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs are primarily used for their potent anti-inflammatory effects in disorders of many organ systems.

Glucocorticoids cause profound and varied metabolic effects. In addition, they modify the body’s immune responses to diverse stimuli.

Last reviewed on RxList: 1/6/2005
This monograph has been modified to include the generic and brand name in many instances.