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Cortone

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Cortone

Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Cortone Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Cortisone acetate is a glucocorticoid used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders. The brand name of this medication is discontinued, but generic versions may be available. Common side effects include insomnia, mood changes, acne, dry skin, thinning skin, bruising or discoloration, slow wound healing, increased sweating, headache, dizziness, spinning sensation, nausea, stomach pain, bloating, or changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

The initial dosage of cortisone acetate may vary from 25 to 300 mg per day depending on the specific disease entity being treated. Cortisone acetate may interact with aspirin, diuretic, blood thinners, cyclosporine, insulin or oral diabetes medications, ketoconazole, rifampin, seizure medications, and other drugs. Tell your doctor all medications and supplements you use. It is unknown if cortisone acetate will harm a fetus. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Cortisone can pass into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding.

Our cortisone acetate Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Cortone in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • problems with your vision;
  • swelling, rapid weight gain, feeling short of breath;
  • severe depression, unusual thoughts or behavior, seizure (convulsions);
  • bloody or tarry stools, coughing up blood;
  • pancreatitis (severe pain in your upper stomach spreading to your back, nausea and vomiting, fast heart rate);
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling); or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

  • sleep problems (insomnia), mood changes;
  • acne, dry skin, thinning skin, bruising or discoloration;
  • slow wound healing;
  • increased sweating;
  • headache, dizziness, spinning sensation;
  • nausea, stomach pain, bloating; or
  • changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Cortone (Cortisone Acetate) »

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

Cortone Overview - Patient Information: Side Effects

SIDE EFFECTS: Stomach upset, headache, dizziness, menstrual changes (e.g., delayed/irregular/absent periods), trouble sleeping, increased appetite, or weight gain may occur.

If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor immediately if any of these unlikely but serious side effects occur: black stools, bone/joint pain, easy bruising/bleeding, fast/pounding/irregular heartbeat, increased thirst/urination, mental/mood changes (e.g., depression, mood swings, agitation), muscle pain, persistent weight gain, puffy face, slow wound healing, seizures, signs of infection (e.g., fever, persistent sore throat), stomach/abdominal pain, swelling of the ankles/feet, thinning skin, trouble breathing, unusual hair growth, unusual skin growths, vision changes, vomit that looks like coffee grounds, weakness.

A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for Cortone (Cortisone Acetate)»

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Cortone FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Fluid and electrolyte disturbances

Sodium retention

Potassium loss

Fluid retention

Hypokalemic alkalosis

Congestive heart failure in susceptible patients

Hypertension

Musculoskeletal

Muscle weakness

Vertebral compression fractures

Steroid myopathy

Aseptic necrosis of femoral and humeral heads

Loss of muscle mass

Osteoporosis

Tendon rupture, particularly of the Achilles tendon

Pathologic fracture of long bones

Gastrointestinal

Peptic ulcer with possible perforation and hemorrhage

Abdominal distention

Ulcerative esophagitis

Pancreatitis

Increases in alanine transaminase (ALT, SGPT), aspartate transaminase (AST, SGOT) and alkaline phosphatase have been observed following corticosteroid treatment. These changes are usually small, not associated with any clinical syndrome and are reversible upon discontinuation.

Dermatologic

Impaired wound healing

Facial erythema

Thin fragile skin

Increased sweating

Petechiae and ecchymoses

May suppress reactions to skin tests

Neurological

Increased intracranial pressure with papil-ledema (pseudotumor cerebri) usually after treatment

Convulsions

Vertigo

Headache

Endocrine

Menstrual irregularities

Suppression of growth in children

Development of Cushingoid state

Decreased carbohydrate tolerance

Secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness

Manifestations of latent diabetes mellitus Increased requirements for insulin or oral hypoglycemic agents in diabetics

Ophthalmic

Posterior subcapsular cataracts Glaucoma

Increased intraocular pressure Exophthalmos

Metabolic

Negative nitrogen balance due to protein catabolism

Read the entire FDA prescribing information for Cortone (Cortisone Acetate) »

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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