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CORTROSYN™ (cosyntropin) for Injection is a sterile Iyophilized powder in vials containing 0.25 mg of CORTROSYN™ (cosyntropin) and 10 mg of mannitol to be reconstituted with 1 mL of 0.9% Sodium Chloride Injec-tion, USP. Administration is by intravenous or intramuscular injection. Cosyntropin is α1 - 24 corticotropin, a synthetic subunit of ACTH. It is an open chain polypeptide containing, from the N terminus, the first 24 of the 39 amino acids of natural ACTH. The sequence of amino acids in the 1 - 24 compound is as follows:

Last reviewed on RxList: 9/9/2008
This monograph has been modified to include the generic and brand name in many instances.