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Since CORTROSYN™ (cosyntropin) for Injection is intended for diag-nostic and not therapeutic use, adverse reactions other than a rare hypersensitivity reaction are not anticipated. A rare hypersensitivity reaction usually associated with a pre-existing allergic disease and/or a previous reaction to natural ACTH is possible. Symptoms may include slight whealing with splotchy erythema at the injection site. There have been rare reports of anaphylactic reaction. The following adverse reactions have been reported in patients after the admin-istration of CORTROSYN™ (cosyntropin) and the association has been neither confirmed nor refuted:

• bradycardia
• tachycardia
• hypertension
• peripheral edema
• rash

Corticotropin may accentuate the electrolyte loss associated with diuretic therapy.

Last reviewed on RxList: 9/9/2008
This monograph has been modified to include the generic and brand name in many instances.