"In laboratory tests, researchers have used electrical stimulation of retinal cells to produce the same patterns of activity that occur when the retina sees a moving object. Although more work remains, this is a step toward restoring natural, high"...
COSOPT® is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to beta-blockers (failed to achieve target IOP determined after multiple measurements over time). The IOP-lowering of COSOPT administered twice a day was slightly less than that seen with the concomitant administration of 0.5% timolol administered twice a day and 2% dorzolamide administered three times a day [see Clinical Studies].
DOSAGE AND ADMINISTRATION
The dose is one drop of COSOPT in the affected eye(s) two times daily.
If more than one topical ophthalmic drug is being used, the drugs should be administered at least five minutes apart [see DRUG INTERACTIONS].
Dosage Forms And Strengths
Solution containing 20 mg/mL dorzolamide (22.26 mg of dorzolamide hydrochloride) and 5 mg/mL timolol (6.83 mg timolol maleate).
Storage And Handling
COSOPT Ophthalmic Solution is supplied in an OCUMETER® PLUS container, a white, translucent, HDPE plastic ophthalmic dispenser with a controlled drop tip and a white polystyrene cap with dark blue label as follows:
NDC 17478-605-10, 10 mL in an 18 mL capacity bottle.
Store COSOPT at 15° to 30°C (59° to 86°F). Protect from light.
Distributed by: Akorn, Inc., Lake Forest, IL 60045 Made in France. Revised: Jan 2015This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 11/4/2016
Additional Cosopt Information
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