"The US Food and Drug Administration has expanded the use of the protease inhibitor darunavir (Prezista, Janssen Therapeutics) to pregnant women with HIV infection, the company announced.
Darunavir is already indicated for tre"...
Crixivan Patient Information Including Side Effects
Brand Names: Crixivan
Generic Name: indinavir (Pronunciation: in DIN a veer)
- What is indinavir (Crixivan)?
- What are the possible side effects of indinavir (Crixivan)?
- What is the most important information I should know about indinavir (Crixivan)?
- What should I discuss with my healthcare provider before taking indinavir (Crixivan)?
- How should I take indinavir (Crixivan)?
- What happens if I miss a dose (Crixivan)?
- What happens if I overdose (Crixivan)?
- What should I avoid while taking indinavir (Crixivan)?
- What other drugs will affect indinavir (Crixivan)?
- Where can I get more information?
What is indinavir (Crixivan)?
Indinavir is an antiviral medication in a group of HIV medicines called protease (PRO-tee-ayz) inhibitors. Indinavir prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
Indinavir is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Indinavir is not a cure for HIV or AIDS.
Indinavir may also be used for purposes not listed in this medication guide.
Crixivan 200 mg
capsule, white, imprinted with CRIXIVAN, 200 mg
Crixivan 400 mg
capsule, white, imprinted with CRIXIVAN, 400 mg
What are the possible side effects of indinavir (Crixivan)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking indinavir and call your doctor at once if you have any of these serious side effects:
- pain in your side or lower back, blood in your urine;
- pale skin, easy bruising or bleeding, confusion or weakness;
- signs of a new infection, such as fever or chills, cough, or flu symptoms;
- rapid heart rate, increased sweating, tremors in your hands, anxiety, feeling irritable, sleep problems (insomnia);
- diarrhea, unexplained weight loss, menstrual changes, impotence, loss of interest in sex;
- swelling in your neck or throat (enlarged thyroid);
- muscle weakness, tired feeling, joint or muscle pain, feeling short of breath;
- weakness or prickly feeling in your fingers or toes;
- problems with walking, breathing, speech, swallowing, or eye movement;
- severe lower back pain, loss of bladder or bowel control;
- nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- high blood sugar -- increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision; or
- severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Less serious side effects may include:
- mild nausea, vomiting;
- numbness or tingling, especially around your mouth;
- headache, mood changes; or
- changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Crixivan (indinavir sulfate) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about indinavir (Crixivan)?
Life-threatening side effects may occur if you take indinavir with alfuzosin (Uroxatral), amiodarone (Cordarone, Pacerone), cisapride (Propulsid), pimozide (Orap), alprazolam (Xanax), oral midazolam (Versed), triazolam (Halcion), lovastatin (Mevacor, Altoprev, Advicor), simvastatin (Zocor, Simcor, Vytorin, Juvisync), sildenafil (Revatio, for treating pulmonary arterial hypertension), or ergot medicines such as ergotamine (Ergomar, Cafergot), dihydroergotamine (D.H.E. 45, Migranal Nasal Spray), ergonovine (Ergotrate), or methylergonovine (Methergine).
There are many other drugs that can cause serious medical problems if you take them together with indinavir. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.
Taking this medication will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.
Additional Crixivan Information
- Crixivan Drug Interactions Center: indinavir oral
- Crixivan Side Effects Center
- Crixivan Overview including Precautions
- Crixivan FDA Approved Prescribing Information including Dosage
Crixivan - User Reviews
Crixivan User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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