"Entry Inhibitors (including Fusion Inhibitors) and CCR5 Co-receptor Antagonist
Entry inhibitors block HIV entry into CD4+ cells.
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Crixivan Patient Information Including Side Effects
Brand Names: Crixivan
Generic Name: indinavir (Pronunciation: in DIN a veer)
- What is indinavir (Crixivan)?
- What are the possible side effects of indinavir (Crixivan)?
- What is the most important information I should know about indinavir (Crixivan)?
- What should I discuss with my healthcare provider before taking indinavir (Crixivan)?
- How should I take indinavir (Crixivan)?
- What happens if I miss a dose (Crixivan)?
- What happens if I overdose (Crixivan)?
- What should I avoid while taking indinavir (Crixivan)?
- What other drugs will affect indinavir (Crixivan)?
- Where can I get more information?
What is indinavir (Crixivan)?
Indinavir is an antiviral medication in a group of HIV medicines called protease (PRO-tee-ayz) inhibitors. Indinavir prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
Indinavir is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Indinavir is not a cure for HIV or AIDS.
Indinavir may also be used for other purposes not listed in this medication guide.
Crixivan 200 mg
white, imprinted with CRIXIVAN, 200 mg
Crixivan 400 mg
white, imprinted with CRIXIVAN, 400 mg
What are the possible side effects of indinavir (Crixivan)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking indinavir and call your doctor at once if you have any of these serious side effects:
- fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
- pale or yellowed skin, dark colored urine, fever, confusion or weakness;
- increased urination or extreme thirst;
- pain in your side or lower back, blood in your urine;
- easy bruising or bleeding;
- signs of a new infection, such as fever or chills, cough, or flu symptoms; or
- nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
- mild nausea, vomiting, diarrhea, bloating;
- numbness or tingling, especially around your mouth;
- tired feeling;
- headache, mood changes; or
- changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the Crixivan (indinavir sulfate) Side Effects Center for a complete guide to possible side effects »
What is the most important information I should know about indinavir (Crixivan)?
Do not take indinavir with amiodarone (Cordarone, Pacerone), cisapride (Propulsid), pimozide (Orap), alprazolam (Xanax), oral midazolam (Versed), triazolam (Halcion), or an ergot medicine such as Ergomar, Cafergot, Wigraine, D.H.E. 45, Migranal, Methergine.
These drugs can cause life-threatening side effects if you use them while you are taking indinavir.
There are many other medicines that can interact with indinavir. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
HIV/AIDS is usually treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Do not change your doses or medication schedule without advice from your doctor. Every person with HIV or AIDS should remain under the care of a doctor.
Taking indinavir will not prevent you from passing HIV to other people through unprotected sex or sharing of needles. Talk with your doctor about safe methods of preventing HIV transmission during sex, such as using a condom and spermicide. Sharing drug or medicine needles is never safe, even for a healthy person.
Additional Crixivan Information
Crixivan - User Reviews
Crixivan User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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