"The cystic fibrosis (CF) drug Orkambi (Vertex Pharmaceuticals) has received a green light from the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP).
Orkambi is a fixed-dose oral combination "...
- Advise patients to contact their physician immediately if
they experience unusual bruising or bleeding (e.g., nosebleeds, excessive bleeding
after brushing teeth, the appearance of blood in stools or urine, excessive
menstrual bleeding, petechiae, excessive bruising or persistent oozing from
superficial injuries) after hospital discharge.
- Such bruising or bleeding may occur for up to 1 week or longer following initial treatment.
- Advise patients to contact their physician immediately if they experience any signs and symptoms of delayed allergic reactions or serum sickness (e.g., rash, pruritus, urticaria) after hospital discharge.
Last reviewed on RxList: 4/17/2015
This monograph has been modified to include the generic and brand name in many instances.
Additional Crofab Information
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