"The cystic fibrosis (CF) drug Orkambi (Vertex Pharmaceuticals) has received a green light from the European Medicines Agency (EMA) Committee for Medicinal Products for Human Use (CHMP).
Orkambi is a fixed-dose oral combination "...
The maximum amount of CroFab® that can safely be administered in single or multiple doses has not been determined. Doses of up to 18 vials (approximately 13.5 g of protein) have been administered without any observed direct toxic effect.
CroFab® should not be administered to patients with a known history of hypersensitivity to papaya or papain unless the benefits outweigh the risks and appropriate management for anaphylactic reactions is readily available.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 4/17/2015
Additional Crofab Information
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