How is Crohn's Disease Different from Ulcerative Colitis?
Both Crohn's disease and ulcerative colitis are chronic diseases of intestinal inflammation. Whereas ulcerative colitis only involves the colonic portion of the gastrointestinal tract, Crohn's disease can affect any portion of the gastrointestinal tract from mouth to anus.
Whereas the inflammation of ulcerative colitis involves only the superficial lining of the colon, the inflammation of Crohn's disease goes deeper into the intestinal walls and, as previously mentioned, even beyond the walls.
Inflammation in ulcerative colitis is continuous, that is, the inflammation does not skip areas. Thus, the colon is involved from the most proximal margin of the inflammation - be that ascending, transverse or sigmoid colon - all the way to the anus. On the other hand, the inflammation of Crohn's disease can be present in several portions of the intestines with skipped areas without inflammation in between.