April 26, 2017
Recommended Topic Related To:

Cubicin RF

"Although Zika virus infections in Puerto Rico occur among males and females of all ages, women are more likely than men to be infected, according to a new report published in the November 10 issue of the Morbidity and Mortality Weekly Report"...

A A A

Cubicin RF

CUBICIN®
(daptomycin) Injection

DRUG DESCRIPTION

CUBICIN RF (daptomycin for injection) contains daptomycin, a cyclic lipopeptide antibacterial agent derived from the fermentation of Streptomyces roseosporus. The chemical name is N-decanoyl-Ltryptophyl- D-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-Dseryl- threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine ε1-lactone. The chemical structure is:

CUBICIN®(daptomycin)Structural Formula Illustration

The empirical formula is C72H101N17O26; the molecular weight is 1620.67. CUBICIN RF is supplied in a single-dose vial as a sterile, preservative-free, pale yellow to light brown, lyophilized powder containing 500 mg of daptomycin for intravenous (IV) use following reconstitution [see DOSAGE AND ADMINISTRATION]. Each vial also contains 713 mg sucrose and sodium hydroxide is used to adjust the pH. The pH of the solution upon reconstitution is 6.8. Freshly reconstituted solutions of CUBICIN RF range in color from pale yellow to light brown.

Last reviewed on RxList: 4/13/2017
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Women's Health

Find out what women really need.