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home > drugs a-z list > cuprimine (penicillamine) drug center > cuprimine (penicillamine) drug - overdosage and contraindications
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Rheumatoid arthritis (RA) facts
- Rheumatoid arthritis is an autoimmune disease that can cause chronic inflammation of the joints and other areas of the body.
- Rheumatoid arthritis can affect people of all ages.
- The cause of rheumatoid arthritis is not known.
- Rheumatoid arthritis is a chronic disease, characterized by periods of disease flares and remissions.
- In rheumatoid arthritis, multiple joints are usually, but not always, affected in a symmetrical pattern.
- Chronic inflammation of rheumatoid arthritis can cause permanent joint destruction and deformity.
- Damage to joints can occur early and does not correlate with the severity of symptoms.
- The "rheumatoid factor" is an antibody that can be found in the blood of 80% of people with rheumatoid arthritis.
- There is no known cure for rheumatoid arthritis.
- The treatment of rheumato...
Cuprimine
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CONTRAINDICATIONS
Except for the treatment of Wilson's disease or certain patients with cystinuria, use of penicillamine during pregnancy is contraindicated (see WARNINGS).
Although breast milk studies have not been reported in animals or humans, mothers on therapy with penicillamine should not nurse their infants.
Patients with a history of penicillamine-related aplastic anemia or agranulocytosis should not be restarted on penicillamine (see WARNINGS and ADVERSE REACTIONS).
Because of its potential for causing renal damage, penicillamine should not be administered to rheumatoid arthritis patients with a history or other evidence of renal insufficiency.
Last reviewed on RxList: 12/17/2008
This monograph has been modified to include the generic and brand name in many instances.
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