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CUROSURF® (poractant alfa) Intratracheal Suspension is a sterile, non-pyrogenic pulmonary surfactant intended for intratracheal use only. It is an extract of natural porcine lung surfactant consisting of 99% polar lipids (mainly phospholipids) and 1 % hydrophobic low molecular weight proteins (surfactant associated proteins SP-B and SP-C).

It is suspended in 0.9% sodium chloride solution. The pH is adjusted as required with sodium bicarbonate to a pH of 6.2 (5.5 - 6.5).

CUROSURF (poractant alfa) contains no preservatives.

CUROSURF is a white to creamy white suspension of poractant alfa. Each milliliter of suspension contains 80 mg of surfactant (extract) that includes 76 mg of phospholipids and 1 mg of protein of which 0.2 mg is SP-B. The amount of phospholipids is calculated from the content of phosphorus and contains 55 mg of phosphatidylcholine of which 30 mg is d ipa Imitoyl phosphatidylcholine.

Last reviewed on RxList: 12/4/2008
This monograph has been modified to include the generic and brand name in many instances.