Cyanocobalamin (Cyanocobalamin) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 9, 2012

Cyanocobalamin

Celiac Disease »

Celiac disease facts

Celiac disease is a chronic digestive disorder in which damage to the lining of the small intestine leads to the malabsorption of minerals and nutrients.
The destruction of the inner lining of the small intestine in celiac disease is caused by an immunological (allergic) reaction to gluten.
Gluten is a family of proteins present in wheat, barley, rye, and sometimes oats.
Individuals with celiac disease may develop diarrhea, steatorrhea, weight loss, flatulence, iron deficiency anemia, abnormal bleeding, or weakened bones. However, many adults with celiac disease may have either no symptoms or only vague abdominal discomfort such as bloating, abdominal distension, and excess gas.
Children with celiac disease may have stunted growth, and if untreated, childhood celiac disease can result in short stature as an adult.
...

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Cyanocobalamin

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Cyanocobalamin
Injection, USP

DRUG DESCRIPTION

Cyanocobalamin Injection, USP is a sterile solution of cyanocobalamin for intramuscular or subcutaneous injection. Each mL contains 1000 mcg cyanocobalamin.

Each vial also contains Sodium Chloride, 0.9%. Benzyl Alcohol, 1.5%, is present as a preservative. Sodium hydroxide and/or hydrochloric acid may have been added during manufacture to adjust the pH (range 4.5-7.0).

Cyanocobalamin appears as dark red crystals or as an amorphous or crystalline red powder. It is very hygroscopic in the anhydrous form, and sparingly soluble in water (1:80). It is stable to autoclaving for short periods at 121°C. The vitamin B₁₂ coenzymes are very unstable in light.

The chemical name is 5,6-dimethyl-benzimidazolyl cyanocobamide; the molecular formula is C₆₃H₈₈C₀N₁₄O₁₄P. The cobalt content is 4.34%. The molecular weight is 1355.39.

The structural formula is represented below.

Cyanocobalamin Structural Formula Illustration

What are the precautions when taking cyanocobalamin (Cyanocobalamin)?

Before using cyanocobalamin, tell your doctor or pharmacist if you are allergic to it; or to cobalt; or if you have any other allergies. Your doctor may recommend that you receive a smaller test dose before starting your regular dose. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: low potassium blood levels (hypokalemia), gout, a certain blood disorder (polycythemia vera), a certain eye disease (Leber's disease), other vitamin/mineral deficiencies (especially folic acid and iron).

This product may contain aluminum, which can infrequently build up to dangerous levels in the body. The...

Read All Potential Precautions of Cyanocobalamin »

Last reviewed on RxList: 10/23/2008
This monograph has been modified to include the generic and brand name in many instances.