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Cyanokit

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Cyanokit

Cyanokit Patient Information Including Side Effects

Brand Names: Cyanokit, Hydroxocobalamin

Generic Name: hydroxocobalamin (injection) (Pronunciation: hye DROX o koe BAL a min)

What is hydroxocobalamin (Cyanokit)?

Hydroxocobalamin is a form of vitamin B-12. It is used as an antidote to cyanide poisoning. Hydroxocobalamin works by helping cells in the body convert cyanide to a form that can be removed from the body through urination.

Hydroxocobalamin is used in an emergency to treat cyanide poisoning. This type of poisoning can occur if you are exposed to smoke from a house or industrial fire, if you swallow or breathe in cyanide, or if you get cyanide on your skin.

Hydroxocobalamin may also be used for purposes not listed in this medication guide.

What are the possible side effects of hydroxocobalamin (Cyanokit)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; chest tightness, difficulty breathing; swelling of your face, lips, tongue, or throat.

You may develop an acne-like skin rash within 1 to 4 weeks after you are treated with hydroxocobalamin. This rash should go away without treatment. Call your doctor if you have a rash that lasts longer than 4 weeks.

Call your doctor at once if you have a serious side effect such as:

  • bright red blood in your stools;
  • chest pain, fast or uneven heart rate;
  • severe shortness of breath, wheezing, gasping for breath, cough with foamy mucus;
  • swelling in your feet or ankles;
  • feeling like you might pass out; or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

  • red coloring of your urine (may last up to 5 weeks);
  • red coloring of your skin (may last up to 2 weeks);
  • eye redness or irritation;
  • acne, mild skin rash;
  • nausea, vomiting, diarrhea, stomach pain;
  • dry throat, trouble swallowing;
  • headache, dizziness, memory problems, restless feeling;
  • hot flashes; or
  • pain, swelling, or irritation of your skin where the injection was given.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Cyanokit (hydroxocobalamin for injection) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about hydroxocobalamin (Cyanokit)?

If possible before you receive hydroxocobalamin, tell your caregivers if you have high blood pressure, heart disease, congestive heart failure, liver disease, or kidney disease (or if you are on dialysis).

Also tell your caregivers if you have ever had a severe allergic reaction to hydroxocobalamin, Vitamin B12, or cyanocobalamin (Nascobal, Cobolin, Cyomin, and others).

In an emergency situation it may not be possible before you are treated to tell your caregivers about your health conditions or if you are pregnant or breast feeding. Make sure any doctor caring for you afterward knows that you have received this medication.

This medication can cause unusual results with certain medical tests. Tell any doctor who treats you that you have recently received a hydroxocobalamin injection.

You may develop an acne-like skin rash within 1 to 4 weeks after you are treated with hydroxocobalamin. This rash should go away without treatment. Call your doctor if you have a rash that lasts longer than 4 weeks.

If your skin turns red after receiving this medication, avoid exposure to sunlight or tanning beds. Hydroxocobalamin can make you sunburn more easily while your skin is still red. Wear protective clothing and use sunscreen (SPF 30 or higher) until your skin color returns to normal.

Side Effects Centers
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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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