Cyclic Vomiting Syndrome (CVS)
- Cyclic vomiting syndrome facts*
- What is cyclic vomiting syndrome?
- What are the symptoms of cyclic vomiting syndrome?
- What triggers cyclic vomiting syndrome?
- What are the four phases of cyclic vomiting syndrome?
- How is cyclic vomiting syndrome diagnosed?
- How is cyclic vomiting syndrome treated?
- What are the complications if cyclic vomiting syndrome is not treated?
- What is the relationship between cyclic vomiting syndrome and migraines?
- What other features and conditions accompany cyclic vomiting syndrome?
- How common is cyclic vomiting syndrome?
- What are the genetic changes related to cyclic vomiting syndrome?
- How do people inherit cyclic vomiting syndrome?
- What other names do people use for cyclic vomiting syndrome?
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Cyclic vomiting syndrome facts*
*Cyclic vomiting syndrome facts medical author: Charles Patrick Davis, MD, PhD
- Cyclic vomiting syndrome is a disorder that causes recurrent episodes of nausea, vomiting, and tiredness (lethargy) most often in children but may occur in all age groups.
- Symptoms of cyclic vomiting syndrome are repeated attacks of intense nausea, vomiting, and lethargy that last anywhere from an hour to 10 days; other symptoms may include pale skin, abdominal pain, diarrhea, headache, and an increased sensitivity to light or to sound.
- The most common situations that cause cyclic vomiting syndrome are emotional excitement and infections; other triggers can include periods without eating, temperature extremes, lack of sleep, overexertion, allergies, ingesting certain foods or alcohol, and menstruation.
- Cyclic vomiting syndrome has four phases: symptom-free, prodrome, vomiting, and recovery.
- Cyclic vomiting syndrome is diagnosed by the patient's history and symptoms.
- Treatment is done by the patient learning to avoid the causes or triggers of the disorder; however, during the prodrome, vomiting and recovery phases, medications are often used to treat the symptoms (for example, anti-nausea medications, NSAIDs, anti-migraine medications, fluid replenishment and others).
- Complications may include pain, reflux, fainting, depression, panic disorder, and irritable bowel syndrome.
- Cyclic vomiting syndrome is generally considered to be a variant of migraines by researchers.
- "Cyclic vomiting syndrome plus" is considered a diagnosis when a patients also exhibit symptoms of developmental delay or intellectual disability, muscle weakness (myopathy), and/or seizures.
- The disorder has a wide range of reported prevalence, about 4 to 2000 per 100,000 children; but seems to occur less frequently in adults although the data is not clear.
- Researchers suggest several factors may contribute to the disorder: brain function disorder, hormonal abnormalities, GI problems, migraine-like conditions, and changes in mitochondrial DNA.
- Some people may inherit the changes in mitochondrial DNA that may cause the disorder.
What is cyclic vomiting syndrome?
Cyclic vomiting syndrome is a disorder that causes recurrent episodes of nausea, vomiting, and tiredness (lethargy). This condition is diagnosed most often in young children, but it can affect people of any age.
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