November 27, 2015
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"More than 29 million Americans have diabetes, and about 86 million more are on the verge of the disease. People with diabetes are nearly two times more likely than people without diabetes to die from heart disease, and are also at greater ris"...



(Bromocriptine Mesylate) Tablets

Read the Patient Information before you start taking CYCLOSET and each time you get a refill. There may be new information. This information does not take the place of talking with your healthcare provider about your medical condition or treatment.


CYCLOSET is a prescription medicine used with diet and exercise to lower blood sugar in adults with type 2 diabetes. CYCLOSET may be taken alone or with other medicines that also help to control blood sugar.

CYCLOSET has not been studied in children.

Who should not take CYCLOSET?

Do not take CYCLOSET if you:

  • are allergic to bromocriptine or any of the other ingredients in CYCLOSET
  • take ergot medicines. Ask your healthcare provider for a list of these medicines, if you are not sure
  • are breastfeeding
  • have fainting (syncopal) migraine headaches

Talk to your healthcare provider before taking CYCLOSET if you have any of these conditions.

What should I tell my healthcare provider before taking CYCLOSET?

Before taking CYCLOSET, tell your healthcare provider about all of your medical conditions, including if you:

  • have Type 1 diabetes mellitus
  • have diabetic ketoacidosis
  • have ever passed out or fainted
  • have migraine headaches
  • have or have had low blood pressure (hypotension)
  • have or have had a mental health condition, especially a psychotic disorder
  • are pregnant or plan to become pregnant. It is not known if CYCLOSET will harm your unborn baby. Talk with your healthcare provider if you are pregnant or plan to become pregnant.

Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take medicines for:

  • mental health conditions, especially anti-psychotic medicines
  • migraine or other types of headaches
  • type 2 diabetes

Ask your healthcare provider or pharmacist for a list of medicines taken for these conditions, if you are not sure.

CYCLOSET may affect the way other medicines work, and other medicines may affect how CYCLOSET works.

Know the medicines you take. Keep a list of your medicines and show it to your healthcare provider and pharmacist when you get a new medicine.

How should I take CYCLOSET?

  • Take CYCLOSET exactly as your healthcare provider tells you to take it.
  • Take CYCLOSET by mouth each day.
  • Take CYCLOSET with food.
  • Take CYCLOSET within 2 hours after waking in the morning.
  • If you miss your morning dose, wait until the next morning to take your medication.
  • Do not take a double dose of CYCLOSET.
  • During periods of stress on the body, such as fever, trauma, infection, or surgery, your medication needs may change. Contact your healthcare provider right away.
  • If you take too much CYCLOSET, call your healthcare provider or go to the nearest emergency department right away.
  • While taking CYCLOSET:
    • check your blood sugar as your healthcare provider tells you to
    • stay on your prescribed diet and exercise program
    • learn to prevent, recognize, and manage low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), and complications of diabetes
    • see your healthcare provider for regular blood tests, including your blood sugar levels and hemoglobin HbA1c

What are the possible side effects of CYCLOSET?

CYCLOSET may cause serious side effects, including:

  • Low blood pressure
  • Fainting
  • Severe dizziness which can be caused by postural hypotension. This can happen when your blood pressure lowers rapidly after you stand up from a lying down position.

The most common side effects of CYCLOSET include:

  • nausea
  • headache
  • fatigue (somnolence). If you have somnolence from CYCLOSET you should not drive or use other heavy machines until the somnolence is better.
  • dizziness
  • vomiting
  • low blood sugar (hypoglycemia), especially when used with another type of diabetes medicine known as a sulfonylurea

Tell your healthcare provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of CYCLOSET. For more information, ask your healthcare provider or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

How Should I store CYCLOSET?

Store CYCLOSET at or below 77°F (25°C)

Keep CYCLOSET and all medicines out of the reach of children.

General information about the use of CYCLOSET

Medicines are sometimes prescribed for conditions that are not mentioned in patient information leaflets. Do not use CYCLOSET for a condition for which it was not prescribed. Do not give CYCLOSET to other people, even if they have the same symptoms you have. It may harm them.

This leaflet summarizes the most important information about CYCLOSET. If you would like more information, talk with your healthcare provider. You can ask your healthcare provider or pharmacist for additional information about CYCLOSET that is written for health professionals. For more information, go to or call 1-877-757-0666.

What are the ingredients in CYCLOSET?

Active ingredient: bromocriptine mesylate Inactive ingredients: lactose, corn starch, magnesium stearate, colloidal silicon dioxide, citric acid, and other inert ingredients

Last reviewed on RxList: 11/5/2015
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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