April 24, 2017
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Cyproheptadine

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Cyproheptadine

Cyproheptadine Hydrochloride
(cyprohepdaine hydrochloride) Tablets USP




DRUG DESCRIPTION

Cyprohepdaine HCl, is an antihistaminic and antiserotonergic agent. Cyproheptadine hydrochloride is a white to slightly yellowish crystalline solid, with a molecular weight of 350.89, which is soluble in water, freely soluble in methanol, sparingly soluble in ethanol, soluble in chloroform, and practically insoluble in ether. It is the sesquihydrate of 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1- methylpiperidine hydrochloride. The molecular formula of the anhydrous salt is C21H21N•HCl and the structural formula of the anhydrous salt is:

Cyproheptadine Hydrochloride - Structural Formula Illustration

Cyproheptadine hydrochloride is available for oral administration in 4 mg tablets. Inactive ingredients include: lactose monohydrate, magnesium stearate, microcrystalline cellulose, and sodium starch glycolate.

What are the possible side effects of cyproheptadine (Periactin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking cyproheptadine and call your doctor at once if you have a serious side effect such as:

  • confusion, hallucinations, unusual thoughts or behavior;
  • seizure (convulsions);
  • ringing in your ears;
  • feeling like you might pass out;
  • fast or pounding heartbeats;
  • easy bruising or bleeding;
  • urinating less than usual or not at all; or
  • pale or yellowed...

Read All Potential Side Effects and See Pictures of Cyproheptadine »

What are the precautions when taking cyproheptadine hydrochloride (Cyproheptadine)?

Before taking cyproheptadine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (such as asthma, emphysema), high pressure in the eye (glaucoma), heart disease, high blood pressure, kidney disease, seizures, stomach/intestine problems (such as ulcers, blockage), overactive thyroid (hyperthyroidism), difficulty urinating (for example, due to enlarged prostate).

This drug may make you dizzy or drowsy or cause blurred vision. Do not drive, use machinery, or do any activity that...

Read All Potential Precautions of Cyproheptadine »

Last reviewed on RxList: 10/10/2016
This monograph has been modified to include the generic and brand name in many instances.

Cyproheptadine - User Reviews

Cyproheptadine User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Cyproheptadine sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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