Cyproheptadine (Cyproheptadine Hydrochloride) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

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Cyproheptadine

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Cyproheptadine Hydrochloride (cyproheptadine (cyproheptadine hydrochloride) hydrochloride)
Tablets, USP

DRUG DESCRIPTION

Cyproheptadine (cyproheptadine hydrochloride) HCl is an antihistaminic and antiserotonergic agent.

Cyproheptadine hydrochloride (cyproheptadine (cyproheptadine hydrochloride) hydrochloride) is a white to slightly yellowish, crystalline solid, which is soluble in water, freely soluble in methanol, sparingly soluble in ethanol, soluble in chloroform, and practically insoluble in ether. It is the sesquihydrate of 4-(5H-dibenzo[a,d] cyclohepten-5-ylidene)-1-methylpiperidine hydrochloride. The molecular and structural formula of the anhydrous salt is:

Cyproheptadine HCl Structural Formula Illustration

C₂₁H₂₁N•HCl..................MW: 350.89

Cyproheptadine (cyproheptadine hydrochloride) HCl is available in tablets for oral administration containing 4 mg of cyproheptadine hydrochloride (cyproheptadine (cyproheptadine hydrochloride) hydrochloride) . Each tablet also contains the following inactive ingredients: dibasic calcium phosphate dihydrate, magnesium stearate, microcrystalline cellulose, polyoxyl (40) stearate, purified water, sodium starch glycolate, and stearic acid.

What are the possible side effects of cyproheptadine (Periactin)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop taking cyproheptadine and call your doctor at once if you have a serious side effect such as:

confusion, hallucinations, unusual thoughts or behavior;
seizure (convulsions);
ringing in your ears;
feeling like you might pass out;
fast or pounding heartbeats;
easy bruising or bleeding;

Read All Potential Side Effects and See Pictures of Cyproheptadine »

What are the precautions when taking cyproheptadine hydrochloride (Cyproheptadine)?

Before taking cyproheptadine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: glaucoma (narrow-angle), stomach problems (e.g., peptic ulcer, stomach/intestinal obstruction), urinary problems (e.g., enlarged prostate, bladder obstruction).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, glaucoma, overactive thyroid, heart disease, high blood pressure, seizure disorder, kidney...

Read All Potential Precautions of Cyproheptadine »

Last reviewed on RxList: 4/3/2009
This monograph has been modified to include the generic and brand name in many instances.