font size

Cystic Fibrosis (cont.)

What are other names for cystic fibrosis?

  • Cystic fibrosis of the pancreas
  • Fibrocystic disease of the pancreas
  • Mucoviscidosis (MU-ko-vis-ih-DO-sis)
  • Mucoviscidosis of the pancreas
  • Pancreas fibrocystic disease
  • Pancreatic cystic fibrosis

What causes cystic fibrosis?

A defect in the CFTR gene causes cystic fibrosis (CF). This gene makes a protein that controls the movement of salt and water in and out of your body's cells. In people who have CF, the gene makes a protein that doesn't work well. This causes thick, sticky mucus and very salty sweat.

Research suggests that the CFTR protein also affects the body in other ways. This may help explain other symptoms and complications of CF.

More than a thousand known defects can affect the CFTR gene. The type of defect you or your child has may affect the severity of CF. Other genes also may play a role in the severity of the disease.

Is cystic fibrosis inherited?

Every person inherits two CFTR genes -- one from each parent. Children who inherit a faulty CFTR gene from each parent will have CF.

Children who inherit one faulty CFTR gene and one normal CFTR gene are "CF carriers." CF carriers usually have no symptoms of CF and live normal lives. However, they can pass the faulty CFTR gene to their children.

The image below shows how two parents who are both CF carriers can pass the faulty CFTR gene to their children.

Example of an Inheritance Pattern for Cystic Fibrosis
Example of an Inheritance Pattern for Cystic Fibrosis

The image shows how CFTR genes are inherited. A person inherits two copies of the CFTR gene -- one from each parent. If each parent has a normal CFTR gene and a faulty CFTR gene, each child has a 25 percent chance of inheriting two normal genes; a 50 percent chance of inheriting one normal gene and one faulty gene; and a 25 percent chance of inheriting two faulty genes.

Medically Reviewed by a Doctor on 3/26/2014

Patient Comments

Viewers share their comments

Cystic Fibrosis - Describe Your Experience Question: Please describe your experience with cystic fibrosis.
Cystic Fibrosis - Symptoms Question: Which cystic fibrosis symptoms have been the most challenging for you or your child?
Cystic Fibrosis - Risk Question: Have you and your spouse/partner been tested for the CF gene? Has or would it affect your decision to conceive?
Cystic Fibrosis - Diagnosis Question: What were the tests that resulted in a cystic fibrosis diagnosis for you, a friend, or relative?
Source: MedicineNet.com
http://www.medicinenet.com/cystic_fibrosis/article.htm

Women's Health

Find out what women really need.

Cystic Fibrosis Related Articles
advertisement
advertisement
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations