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There is no antidote for cytarabine overdosage. Doses of 4.5 g/m2 by intravenous infusion over 1 hour every 12 hours for 12 doses has caused an unacceptable increase in irreversible CNS toxicity and death.
Single doses as high as 3 g/m2 have been administered by rapid intravenous infusion without apparent toxicity.
Cytarabine is contraindicated in those patients who are hypersensitive to the drug.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 11/3/2008
Additional Cytarabine Information
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