"Infants exposed in the womb to a drug used to treat HIV and reduce the transmission of HIV from mother to child, may have lower bone mineral content than those exposed to other anti-HIV drugs, according to a National Institutes of Health study"...
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
GANCICLOVIR - INJECTION
COMMON BRAND NAME(S): Cytovene
WARNING: Ganciclovir can decrease bone marrow function. This serious, possibly life-threatening side effect may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body's ability to fight an infection, and cause bleeding problems. Your doctor will check the results of your blood tests and adjust your treatment to reduce your risk for these side effects. Seek immediate medical attention if you develop signs of anemia (such as unusual tiredness, fast breathing, pale skin, fast heartbeat), signs of infection (such as fever, chills, cough, persistent sore throat), and signs of bleeding (such as easy bruising/bleeding, nose bleeds, bleeding gums, bloody/black/tarry stools, vomit that looks like coffee grounds).
Ganciclovir has caused decreased sperm production in animals and may decrease the ability of men to father a baby.
Ganciclovir has caused tumors in laboratory animals. Although there is no information in humans, ganciclovir should be considered cancer-causing (carcinogenic). See also How to Use and Precautions sections.
USES: Ganciclovir is an anti-viral drug. It is used to prevent disease caused by a virus called cytomegalovirus (CMV) in people who have received organ or bone marrow transplants. CMV disease can lead to serious infections in the body, including an infection in the eye, called CMV retinitis, that can cause blindness.
Ganciclovir is also used to treat people with weakened immune systems (including people with AIDS) who have CMV retinitis. Ganciclovir works by slowing the growth of the CMV virus. It helps control CMV retinitis and decrease the risk of blindness. It also helps prevent the spread of infection to other areas of the body.
Ganciclovir is not a cure for CMV disease. Some people may have worsening CMV retinitis even with treatment. Therefore, it is important to have your eyes checked regularly by your doctor.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This drug may also be used to help prevent CMV disease in patients receiving cancer chemotherapy treatment.
HOW TO USE: This medication is given by injection into a vein usually over a 1-hour period. Do not give this medication any faster than prescribed because doing so will increase the risk of side effects. At the start of treatment, ganciclovir is usually given every 12 hours for the first few weeks, and then once a day either 5 to 7 times a week after that, or as directed by your doctor.
Drink plenty of fluids while using this medication unless your doctor directs you otherwise.
This medication will be prepared by a special pharmacy. If you are using this medication at home, learn all usage instructions from your health care professional. If you have any questions about using this medication properly, consult your health care professional.
Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.
Wear gloves when you handle this medication. Avoid direct contact with the liquid. Avoid getting it on your skin or in your mucous membranes, including your mouth, nose, and eyes. If contact should occur, wash the area thoroughly with soap and water. If this medication gets in your eyes, rinse them thoroughly with plain water.
Learn how to store and discard needles and medical supplies safely. Special disposal is required for this medication and all injection supplies used with it. Consult your pharmacist for more information.
The dosage and length of treatment is based on your weight, medical condition, and response to treatment.
This medication works best when the amount of drug in your body is kept at a constant level. Therefore, use this drug at evenly spaced intervals. To help you remember, use it at the same time(s) each day.
Continue using this medication exactly as prescribed by your doctor. Do not skip any doses or stop using this medication even for a short time unless directed to do so by your doctor. Skipping or stopping treatment without approval from your doctor may make the infection worse.
Keep all medical and laboratory appointments.
Tell your doctor if your condition worsens (such as worsening vision).
Additional Cytovene Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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