D-Mannose

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How does D-mannose work?

D-mannose might treat the deficiency caused by a genetic defect that causes abnormal breakdown and production of mannose. D-mannose might prevent certain kinds of bacteria from sticking to the walls of the urinary tract and causing infection.

Are there safety concerns?

D-mannose appears to be safe for when used orally and appropriately. D-mannose can cause loose stools and bloating. In high doses, it might harm the kidneys.

Do not use d-mannose if:
  • You are pregnant or breast-feeding.
  • You have diabetes.

Dosing considerations for D-mannose.

The appropriate dose of D-mannose depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for d-mannose. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.


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You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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