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Daliresp

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Daliresp

Overdosage
Contraindications

OVERDOSE

Human Experience

No case of overdose has been reported in clinical studies with DALIRESP. During the Phase I studies of DALIRESP, the following symptoms were observed at an increased rate after a single oral dose of 2500 mcg and a single dose of 5000 mcg: headache, gastrointestinal disorders, dizziness, palpitations, lightheadedness, clamminess and arterial hypotension.

Management of Overdose

In case of overdose, patients should seek immediate medical help. Appropriate supportive medical care should be provided. Since roflumilast is highly protein bound, hemodialysis is not likely to be an efficient method of drug removal. It is not known whether roflumilast is dialyzable by peritoneal dialysis.

CONTRAINDICATIONS

The use of DALIRESP is contraindicated in the following condition:

Moderate to severe liver impairment (Child-Pugh B or C) [see CLINICAL PHARMACOLOGY and Use in Special Populations].

Last reviewed on RxList: 9/6/2013
This monograph has been modified to include the generic and brand name in many instances.

Overdosage
Contraindications
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