Recommended Topic Related To:

Dantrium

"Medscape Medical News

March 19, 2013 -- People with low back pain may benefit from a hands-on treatment known as osteopathic manual therapy (OMT) more than they do from ultrasound therapy.

A new study suggests that OMT leads t"...

Dantrium IV

Overdosage
Contraindications

OVERDOSE

Because Dantrium Intravenous must be administered at a low concentration in a large volume of fluid, acute toxicity of Dantrium could not be assessed in animals. In 14-day (subacute) studies, the intravenous formulation of Dantrium was relatively non-toxic to rats at doses of 10 mg/kg/day and 20 mg/kg/day. While 10 mg/kg/day in dogs for 14 days evoked little toxicity, 20 mg/kg/day for 14 days caused hepatic changes of questionable biologic significance.

Symptoms which may occur in case of overdose include, but are not limited to, muscular weakness and alterations in the state of consciousness (e.g., lethargy, coma), vomiting, diarrhea, and crystalluria.

For acute overdosage, general supportive measures should be employed.

Intravenous fluids should be administered in fairly large quantities to avert the possibility of crystalluria. An adequate airway should be maintained and artificial resuscitation equipment should be at hand. Electrocardiographic monitoring should be instituted, and the patient carefully observed. The value of dialysis in Dantrium overdose is not known.

CONTRAINDICATIONS

None.

Last reviewed on RxList: 12/22/2008
This monograph has been modified to include the generic and brand name in many instances.

Overdosage
Contraindications
A A A

Additional Dantrium IV Information

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Chronic Pain/Back Pain

Find tips and advances in treatment.