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Lupus is an autoimmune disease characterized by acute and chronic inflammation of various tissues of the body. Autoimmune diseases are illnesses that occur when the body's tissues are attacked by its own immune system. The immune system is a complex system within the body that is designed to fight infectious agents, such as bacteria and other foreign microbes. One of the ways that the immune system fights infections is by producing antibodies that bind to the microbes. People with lupus produce abnormal antibodies in their blood that target tissues within their own body rather than foreign infectious agents. Because the antibodies and accompanying cells of inflammation can affect tissues anywhere in the body, lupus has the potential to affect a variety of areas. Sometimes lupus can cause disease of the skin, heart, lungs, kidneys, joints, and/or nervous system. When only the skin is involved, the conditi...
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DAPSONE TABLETS USP (Jacobus)
25 mg. & 100 mg.
PRODUCT OVERVIEW
KEY FACTS
Dapsone is a sulfone for the primary treatment of Dermatitis herpetiformis and an antibacterial drug for susceptible cases of leprosy.
MAJOR USES
Dapsone is used to control the dermatologic symptoms of Dermatitis herpetiformis. Dapsone is used alone or in combination with other anti-leprosy drugs for leprosy.
SAFETY INFORMATION
Dapsone is contraindicated in patients with Dapsone hypersensitivity. Complete blood counts and laboratory monitoring should be done frequently. See labeling.
PRODUCT INFORMATION
Dapsone-USP, 4,4'-diaminodiphenylsulfone (DDS) is a primary treatment for Dermatitis herpetiformis. It is an antibacterial drug for susceptible cases of leprosy. It is a white, odorless crystalline powder, practically insoluble in water and insoluble in fixed and vegetable oils.
Dapsone is issued on prescription in tablets of 25 and 100 mg. for oral use.
Inactive Ingredients: Colloidal silicone dioxide, magnesium stearate, microcrystalline cellulose, and corn starch.
In rare cases, dapsone has been associated with serious, and sometimes fatal blood and/or liver problems. Contact your doctor immediately if you experience a sore throat, fever, pale skin, bruising or pinpoint red spots on the skin, or yellowing of the skin or eyes. These may be symptoms of blood or liver problems.
Contact your doctor immediately if you develop a rash while taking dapsone. In rare cases, dapsone has been associated with serious, and sometimes fatal, skin reactions.
If you experience any of the following serious side effects, seek...
Read All Potential Side Effects and See Pictures of Dapsone »
Before taking dapsone, tell your doctor or pharmacist if you are allergic to it; or to similar drugs such as sulfoxone; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
This medication should not be used if you have a certain medical condition. Before using this medicine, consult your doctor or pharmacist if you have: severe anemia.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain blood disorders (e.g., G6PD deficiency, methemoglobin reductase deficiency), liver disease, severe heart disease, severe lung disease, serious infection, very high blood sugar (diabetic ketosis).
If using...
Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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