"Nov. 2, 2012 -- Safety steps taken in the wake of the fungal meningitis outbreak have worsened drug shortages, raising questions about whether the U.S. must choose between the safety and the availability of crucial medicines.
(Generic versions may still be available.)
In a survey conducted in hospitalized patients less than 1% of patients taking propoxyphene hydrochloride at recommended doses experienced side effects. The most frequently reported were dizziness, sedation, nausea and vomiting. Some of these adverse reactions may be alleviated if the patient lies down.
Read the Darvon Compound (propoxyphene, aspirin, and caffeine) Side Effects Center for a complete guide to possible side effects
Salicylates may enhance the effect of anticoagulants and inhibit the uric-casework effect of uricosuric agents.
As is the case with many medicinal agents propoxyphene may slow the metabolism of a concomitantly administered drug. Should this occur the higher serum concentrations of that drug may result in increased pharmacologic or adverse effects of that drug. Such occurrences have been reported when propoxyphene was administered to patients on antidepressants, anticonvulsants, or warfarin-like drugs. Severe neurologic signs, including coma have occurred with concurrent use of carbamazepine.
Last reviewed on RxList: 1/29/2005
This monograph has been modified to include the generic and brand name in many instances.
Additional Darvon Compound Information
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