"Nov. 2, 2012 -- Safety steps taken in the wake of the fungal meningitis outbreak have worsened drug shortages, raising questions about whether the U.S. must choose between the safety and the availability of crucial medicines.
(Generic versions may still be available.)
Darvon Patient Information including If I Miss a Dose
In this Article
- What is propoxyphene (Darvon)?
- What are the possible side effects of propoxyphene (Darvon)?
- What is the most important information I should know about propoxyphene (Darvon)?
- What should I tell my healthcare provider before taking propoxyphene (Darvon)?
- How should I take propoxyphene (Darvon)?
- What happens if I miss a dose (Darvon)?
- What happens if I overdose (Darvon)?
- What should I avoid while taking propoxyphene (Darvon)?
- What other drugs will affect propoxyphene (Darvon)?
- Where can I get more information?
What happens if I miss a dose (Darvon)?
Since propoxyphene is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose (Darvon)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of propoxyphene can be fatal, especially if you are also drinking alcohol or taking a sedative or antidepressant.
Overdose symptoms may include extreme drowsiness, pinpoint or dilated pupils, confusion, cold and clammy skin, blue lips, weak pulse, slow or uneven heart rate, shallow breathing, fainting, or breathing that stops.
What should I avoid while taking propoxyphene (Darvon)?
Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with a narcotic pain medicine. Check your food and medicine labels to be sure these products do not contain alcohol.
Propoxyphene may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Grapefruit and grapefruit juice may interact with propoxyphene and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
What other drugs will affect propoxyphene (Darvon)?
Do not take propoxyphene with other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result.
Tell your doctor about all other medicines you use, especially:
- amiodarone (Cordarone, Pacerone);
- aprepitant (Emend);
- bosentan (Tracleer);
- conivaptan (Vaprisol);
- dexamethasone (Decadron, Hexadrol);
- imatinib (Gleevec);
- isoniazid (for treating tuberculosis);
- St. John's wort;
- an antibiotic such as clarithromycin (Biaxin), dalfopristin/quinupristin (Synercid), erythromycin (E.E.S., EryPed, Ery-Tab, Erythrocin), rifampin (Rifadin, Rifater, Rifamate), or telithromycin (Ketek);
- antifungal medication such as clotrimazole (Mycelex Troche), fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), or voriconazole (Vfend);
- an antidepressant such as nefazodone;
- a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Solfoton);
- a blood thinner such as warfarin (Coumadin);
- heart or blood pressure medication such as diltiazem (Cartia, Cardizem), felodipine (Plendil), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others;
- HIV/AIDS medicine such as atazanavir (Reyataz), delavirdine (Rescriptor), efavirenz (Sustiva), etravirine (Intelence), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), saquinavir (Invirase), or ritonavir (Norvir);
- medicines to treat narcolepsy, such as armodafanil (Nuvigil) or modafanil (Progivil); or
- seizure medication such as carbamazepine (Carbatrol, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), or phenytoin (Dilantin), or primidone (Mysoline).
This list is not complete and other drugs may interact with propoxyphene. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about propoxyphene.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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