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DDAVP Injection

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DDAVP Injection

DDAVP® Injection
(desmopressin acetate) 4 mcg/mL

DDAVP Injection

DRUG DESCRIPTION

DDAVP® Injection (desmopressin acetate) 4 mcg/mL is a synthetic analogue of the natural pituitary hormone 8-arginine vasopressin (ADH), an antidiuretic hormone affecting renal water conservation. It is chemically defined as follows:

Mol. Wt. 1183.34.............................Empirical Formula: C46H64N14O12S2•C2H4O2•3H2O

DDAVP® (desmopressin acetate)  structural formula illustration

1-(3-mercaptopropionic acid)-8-D-arginine vasopressin monoacetate (salt) trihydrate.

DDAVP Injection (desmopressin acetate injection) 4 mcg/mL is provided as a sterile, aqueous solution for injection. Each mL provides:

Desmopressin acetate 4.0 mcg
Sodium chloride          9.0 mg
Hydrochloric acid to adjust pH to 4.

The 10 mL vial contains chlorobutanol as a preservative (5.0 mg/mL).

What are the possible side effects of desmopressin (DDAVP)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using desmopressin and call your doctor at once if you have any of these serious side effects:

  • nausea, vomiting, weakness, loss of appetite, headache, feeling restless or irritable, confusion, hallucinations, muscle pain or weakness, and/or seizure;
  • feeling like you might pass out;
  • swelling;
  • chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating,...

Read All Potential Side Effects and See Pictures of DDAVP Injection »

What are the precautions when taking desmopressin acetate injection (DDAVP Injection)?

Before using desmopressin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: kidney disease, a low level of sodium in the blood (current or past hyponatremia).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: high or low blood pressure, heart disease (such as blocked blood vessels in the heart), conditions that may increase your risk of fluid/mineral imbalance (such as cystic fibrosis, heart...

Read All Potential Precautions of DDAVP Injection »

Last reviewed on RxList: 2/12/2008
This monograph has been modified to include the generic and brand name in many instances.

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DDAVP Injection - User Reviews

DDAVP Injection User Reviews

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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