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DDAVP Nasal Spray

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DDAVP Nasal Spray

DDAVP Nasal Spray Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

DDAVP Nasal Spray (desmopressin acetate) is used to treat central cranial diabetes insipidus, increased thirst and urination caused by head surgery or head trauma, hemophilia A, or von Willebrand's disease Type I. It is a man-made form of a hormone that occurs naturally in the pituitary gland. This medication is available in generic form. Common side effects include headache, runny/stuffy nose, nausea, upset stomach, or flushing of the face.

The usual dosage range of DDAVP Nasal Spray in adults is 0.1 to 0.4 mL daily, either as a single dose or divided into two or three doses. For children aged 3 months to 12 years, the usual dosage range is 0.05 to 0.3 mL daily, either as a single dose or divided into two doses. DDAVP Nasal Spray may interact with carbamazepine, chlorpromazine, lamotrigine, oxybutynin, vasopressin, narcotics, antidepressants, antidepressants, medicine to treat erectile dysfunction, drugs to treat high blood pressure or a prostate disorder, beta-blockers, or NSAIDs (non-steroidal anti-inflammatory drugs). During pregnancy, DDAVP Nasal Spray should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Our DDAVP Nasal Spray (desmopressin acetate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Patient Information in Detail?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

DDAVP Nasal Spray in Detail - Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using desmopressin nasal and call your doctor at once if you have any of these serious side effects:

  • nausea, vomiting, weakness, loss of appetite, headache, feeling restless or irritable, confusion, hallucinations, muscle pain or weakness, and/or seizure;
  • feeling like you might pass out;
  • swelling;
  • chest pain, fast or pounding heart rate;
  • vaginal pain;
  • nosebleed; or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

  • runny or stuffy nose;
  • sore throat, cough, or other cold symptoms;
  • eye redness or watering;
  • eye itching or increased sensitivity to light;
  • headache, weakness;
  • feeling dizzy or agitated;
  • nausea, vomiting, stomach pain;
  • hot or cold feeling; or
  • warmth, redness, or tingly feeling in your face.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for DDAVP Nasal Spray (Desmopressin Acetate Nasal Spray) »

What is Patient Information Overview?

A concise overview of the drug for the patient or caregiver from First DataBank.

DDAVP Nasal Spray Overview - Patient Information: Side Effects

SIDE EFFECTS: Headache, runny/stuffy nose, nausea, upset stomach, or flushing of the face may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Desmopressin can infrequently cause a low level of sodium in the blood, which can be serious and possibly life-threatening. Drinking too much water or other fluids increases the risk of having a low level of sodium in the blood. Therefore, follow your doctor's directions for limiting fluids. Seek immediate medical attention if you have any of these unlikely but serious symptoms of a low level of sodium in the blood: loss of appetite, severe nausea, vomiting, severe headache, muscle weakness/spasms/cramps, sudden weight gain, unusual tiredness, unusual severe drowsiness, mental/mood changes (such as confusion, hallucinations, irritability), loss of consciousness, seizures, slow/shallow breathing.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

In the US -

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Read the entire patient information overview for DDAVP Nasal Spray (Desmopressin Acetate Nasal Spray)»

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

DDAVP Nasal Spray FDA Prescribing Information: Side Effects
(Adverse Reactions)

SIDE EFFECTS

Infrequently, high dosages of intranasal DDAVP have produced transient headache and nausea. Nasal congestion, rhinitis and flushing have also been reported occasionally along with mild abdominal cramps. These symptoms disappeared with reduction in dosage. Nosebleed, sore throat, cough and upper respiratory infections have also been reported.

The following table lists the percentage of patients having adverse experiences without regard to relationship to study drug from the pooled pivotal study data for nocturnal enuresis.

ADVERSE REACTION PLACEBO
(N=59)
DDAVP
20 mcg
(N=60)
DDAVP
40 mcg
(N=61)
  % % %
BODY AS A WHOLE
  Abdominal Pain 0 2 2
  Asthenia 0 0 2
  Chills 0 0 2
  Headache 0 2 5
NERVOUS SYSTEM
  Dizziness 0 0 3
RESPIRATORY SYSTEM
  Epistaxis 2 3 0
  Nostril Pain 0 2 0
  Rhinitis 2 8 3
DIGESTIVE SYSTEM
  Gastrointestinal Disorder 0 2 0
  Nausea 0 0 2
SPECIAL SENSES
  Conjunctivitis 0 2 0
  Edema Eyes 0 2 0
  Lachrymation Disorder 0 0 2

Post Marketing: There have been rare reports of hyponatremic convulsions associated with concomitant use with the following medications: oxybutinin and imipramine.

See WARNINGS for the possibility of water intoxication and hyponatremia.

Read the entire FDA prescribing information for DDAVP Nasal Spray (Desmopressin Acetate Nasal Spray) »

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DDAVP Nasal Spray - User Reviews

DDAVP Nasal Spray User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication DDAVP Nasal Spray sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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