"There is a risk for dosing errors with the dual antibacterial ceftolozane/tazobactam (Zerbaxa, Cubist Pharmaceuticals) due to confusion about the drug strength displayed on the vial and carton labeling, the US Food and Drug Administration "...
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
DEMECLOCYCLINE - ORAL
COMMON BRAND NAME(S): Declomycin
USES: Demeclocycline is used to treat a wide variety of bacterial infections, including those that cause acne. This medication is known as a tetracycline antibiotic. It works by stopping the growth of bacteria.
This antibiotic treats only bacterial infections. It will not work for viral infections (e.g., common cold, flu). Unnecessary use or misuse of any antibiotic can lead to its decreased effectiveness.
OTHER USES: This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.
This drug may also be used for treating a certain hormone imbalance (Syndrome of Inappropriate Antidiuretic Hormone-SIADH) which causes your body to retain water and your urine to be more concentrated than it should be. Demeclocycline works by increasing the amount of water in your urine to more normal levels.
HOW TO USE: Take this medication by mouth, usually 2 to 4 times a day or as directed by your doctor. Demeclocycline works best when taken on an empty stomach at least 1 hour before or 2 hours after a meal. Take each dose with a full glass of water (8 ounces or 240 milliliters) unless your doctor directs you otherwise. Do not lie down for 10 minutes after taking this drug. For this reason, do not take it right before bedtime.
If stomach upset occurs, ask your doctor if you can take this medication with food.
Take this medication 2 to 3 hours before or after taking any medications containing magnesium, aluminum, or calcium. Some examples include quinapril, certain forms of didanosine (chewable/dispersible buffered tablets or pediatric oral solution), vitamins/minerals, and antacids. Dairy products (e.g., milk, yogurt), calcium-enriched juice, sucralfate, bismuth subsalicylate, iron, and zinc are also included. These products bind with demeclocycline, preventing its full absorption.
The dosage is based on your medical condition and response to treatment. When treating children over 8 years of age, the dosage is also based on weight. For the treatment of infection, children should not take more than 600 milligrams of this medication per day.
This medication works best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals.
If you are taking this medication to treat an infection, continue to take it until the full prescribed amount is finished, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.
Inform your doctor if your condition persists or worsens. If you are using this medication to treat SIADH, you should notice an increase in the amount of urine within 5 days.
Additional Declomycin Information
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