Definity (Perflutren Lipid Microsphere) Drug Information: Medication Guide and Patient Information

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May 27, 2012

Definity

Ventricular Septal Defect »

What is a ventricular septal defect (VSD)?

A ventricular septal defect (VSD) is a heart malformation present at birth. Any condition that is present at birth can also be termed a "congenital" condition. A VSD, therefore, is a type of congenital heart disease (CHD). The heart with a VSD has a hole in the wall (the septum) between its two lower chambers (the ventricles).

How common is a VSD?

The most frequent types of congenital malformations affect the heart. It is estimated that approximately eight in 1,000 newborns have CHD. A VSD is the most frequent of the various types of CHD (25%-30% of all CHD). Approximately one infant in 500 will be born with a VSD.

What is the normal design of the heart?

The heart is made up of four separate chambers. The upper right chamber (atrium) receives blood back from the body with much of the oxygen extracted by the body organs and tissues. The blood is...

Read the Ventricular Septal Defect article »

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Heart Disease Slideshow Pictures

Medical Illustrations of the Heart Image Collection

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PATIENT INFORMATION

Patients receiving activated DEFINITY® should be instructed to inform their healthcare provider if they:

have a congenital heart defect, or recent worsening of heart or lung conditions [see CONTRAINDICATIONS and WARNINGS AND PRECAUTION],
have had prior reactions to DEFINITY® [see CONTRAINDICATIONS],
may be pregnant, are trying to become pregnant, or are nursing [see Use In Specific Populations].

Last reviewed on RxList: 11/4/2011
This monograph has been modified to include the generic and brand name in many instances.