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What is a ventricular septal defect (VSD)?

A ventricular septal defect (VSD) is a heart malformation present at birth. Any condition that is present at birth can also be termed a "congenital" condition. A VSD, therefore, is a type of congenital heart disease (CHD). The heart with a VSD has a hole in the wall (the septum) between its two lower chambers (the ventricles).

How common is a VSD?

The most frequent types of congenital malformations affect the heart. It is estimated that approximately eight in 1,000 newborns have CHD. A VSD is the most frequent of the various types of CHD (25%-30% of all CHD). Approximately one infant in 500 will be born with a VSD.

What is the normal design of the heart?

The heart is made up of four separate chambers. The upper right chamber (atrium) receives blood back from the body with much of the oxygen extracted by the body organs and tissues. The blood is...

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OVERDOSE

The clinical consequences of overdosing with activated DEFINITY® are not known. Treatment of an overdose should be directed toward the support of all vital functions and prompt institution of symptomatic therapy [see CONTRAINDICATIONS and WARNINGS AND PRECAUTIONS].

CONTRAINDICATIONS

Do not administer DEFINITY® to patients with known or suspected:

  • Right-to-left, bi-directional, or transient right-to-left cardiac shunts,
  • Hypersensitivity to perflutren [see WARNINGS AND PRECAUTIONS].

Do not administer DEFINITY® by intra-arterial injection.

Last reviewed on RxList: 11/4/2011
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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