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Demadex

"What are diuretics and how do they work?

The amount of fluid (water) retained by the body is controlled primarily by the kidneys. This occurs due to the kidney's ability to control the retention and elimination of sodium and chlorid"...

Demadex

DEMADEX®
(torsemide) Tablets

DRUG DESCRIPTION

DEMADEX (torsemide) is a diuretic of the pyridine-sulfonylurea class. Its chemical name is 1-isopropyl-3-[(4-m-toluidino-3-pyridyl) sulfonyl] urea and its structural formula is:

DEMADEX® (torsemide) Structural Formula Illustration

Its empirical formula is C16H20N4O3S, its pKa is 7.1, and its molecular weight is 348.43.

Torsemide is a white to off-white crystalline powder. The tablets for oral administration also contain lactose NF, crospovidone NF, povidone USP, microcrystalline cellulose NF, and magnesium stearate NF.

What are the possible side effects of torsemide

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • vomiting, fast heartbeats, feeling restless;
  • ringing in your ears, sudden hearing loss;
  • feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin
  • feeling like you might pass out;
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or...

Read All Potential Side Effects and See Pictures of Demadex »

What are the precautions when taking torsemide (Demadex)?

Before taking torsemide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney problems, liver problems, inability to make urine, gout.

If you have diabetes, torsemide may infrequently affect your blood sugar level. Check your blood sugar level regularly as directed and share the results with your doctor. Your doctor may need to adjust your diabetes medication or diet.

Torsemide may reduce the potassium level in your blood. Your doctor may instruct you to add potassium-rich foods to...

Read All Potential Precautions of Demadex »

Last reviewed on RxList: 8/27/2012
This monograph has been modified to include the generic and brand name in many instances.

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Demadex - User Reviews

Demadex User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Demadex sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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