"Nov. 2, 2012 -- Safety steps taken in the wake of the fungal meningitis outbreak have worsened drug shortages, raising questions about whether the U.S. must choose between the safety and the availability of crucial medicines.
(meperidine hydrochloride, USP)
Meperidine hydrochloride is a white crystalline substance with a melting point of 186° C to 189° C. It is readily soluble in water and has a neutral reaction and a slightly bitter taste. The solution is not decomposed by a short period of boiling.
The tablets contain 50 mg or 100 mg of DEMEROL brand of meperidine hydrochloride.
Inactive Ingredients: Calcium Sulfate, Dibasic Calcium Phosphate, Starch, Stearic Acid, Talc.
Chemically, DEMEROL is 4-Piperidinecarboxylic acid, 1-methyl-4-phenyl-, ethyl ester, hydrochloride and has the following structure:
What are the possible side effects of meperidine (Demerol HCl)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- weak or shallow breathing, slow heartbeat;
- severe drowsiness, feeling like you might pass out;
- seizure (convulsions);
- cold, clammy skin;
- muscle movements you cannot control;
- confusion, mood changes;
- severe weakness or dizziness; or
- agitation, hallucinations, fever, fast heart rate,...
What are the precautions when taking meperidine (Demerol)?
Before taking meperidine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before taking this medication, tell your doctor or pharmacist your medical history, especially of: abdominal problems (e.g., gallbladder disease, pancreatitis), adrenal gland problem (e.g., Addison's disease, pheochromocytoma), large blood loss (e.g., recent blood donation, stomach/intestinal bleeding), brain disorders (e.g., seizures, head injury, tumor, increased intracranial pressure), heart problems (e.g., irregular heartbeat, low blood pressure), kidney disease, liver disease, breathing problems (e.g., asthma,...
Last reviewed on RxList: 11/9/2011
This monograph has been modified to include the generic and brand name in many instances.
Additional Demerol Information
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