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Demerol Patient Information Including Side Effects

Brand Names: Demerol HCl

Generic Name: meperidine (Pronunciation: me PER i deen)

What is meperidine (Demerol)?

Meperidine is an opioid pain medication. An opioid is sometimes called a narcotic.

Meperidine is used to treat moderate-to-severe pain.

Meperidine may also be used for purposes not listed in this medication guide.

Demerol 50 mg

round, white, imprinted with W, D 35

Meperidine 100 mg-BAR

round, white, imprinted with barr, 382

Meperidine 100 mg-MAL

round, white, imprinted with 7115, M inside square

Meperidine 100 mg-ROX

round, white, imprinted with 54 163

Meperidine 100 mg-WAT

round, white, imprinted with 727 100, WATSON

Meperidine 50 mg-BAR

round, white, imprinted with 381 b

Meperidine 50 mg-ROX

round, white, imprinted with 54 879

Meperidine 50 mg-WAT

round, white, imprinted with 726 50, WATSON

What are the possible side effects of meperidine (Demerol)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • weak or shallow breathing, slow heartbeat;
  • severe drowsiness, feeling like you might pass out;
  • seizure (convulsions);
  • cold, clammy skin;
  • muscle movements you cannot control;
  • confusion, mood changes;
  • severe weakness or dizziness; or
  • agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting;

Less serious side effects may include:

  • constipation;
  • loss of appetite;
  • headache, dizziness, mild weakness;
  • dry mouth;
  • sweating;
  • itching;
  • urinating less than usual; or
  • loss of interest in sex.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Demerol (meperidine) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about meperidine (Demerol)?

Meperidine may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it.

Do not drink alcohol while you are taking meperidine. Dangerous side effects or death can occur when alcohol is combined with a narcotic pain medicine. Check your food and medicine labels to be sure these products do not contain alcohol.

Never take meperidine in larger amounts, or for longer than recommended by your doctor, or you could have serious or life-threatening side effects. Tell your doctor if the medicine seems to stop working as well in relieving your pain.

This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how meperidine will affect you.

Do not stop using meperidine suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using meperidine.

Side Effects Centers

Demerol - User Reviews

Demerol User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Demerol sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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