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Depo-Provera Patient Information Including Side Effects
Brand Names: Depo-Provera, Depo-Provera Contraceptive, Depo-SubQ Provera 104
Generic Name: medroxyprogesterone (injectable) (Pronunciation: me DROX ee proe JES ter one)
- What is medroxyprogesterone (Depo-Provera)?
- What are the possible side effects of medroxyprogesterone (Depo-Provera)?
- What is the most important information I should know about medroxyprogesterone (Depo-Provera)?
- What should I discuss with my healthcare provider before using medroxyprogesterone (Depo-Provera)?
- How should I use medroxyprogesterone (Depo-Provera)?
- What happens if I miss a dose (Depo-Provera)?
- What happens if I overdose (Depo-Provera)?
- What should I avoid while using medroxyprogesterone (Depo-Provera)?
- What other drugs will affect medroxyprogesterone (Depo-Provera)?
- Where can I get more information?
What is medroxyprogesterone (Depo-Provera)?
Medroxyprogesterone is a form of progesterone, a female hormone that prevents ovulation (the release of an egg from an ovary). This medication also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.
Medroxyprogesterone is used as contraception to prevent pregnancy. It is also used to reduce pain caused by endometriosis.
Medroxyprogesterone is also used to ease pain and other symptoms in women with metastatic uterine or kidney cancer. This medication is not a cure for these conditions.
Medroxyprogesterone may also be used for purposes not listed in this medication guide.
What are the possible side effects of medroxyprogesterone (Depo-Provera)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- menstrual periods that are heavier or longer than normal;
- sudden numbness or weakness, especially on one side of the body;
- sudden severe headache, confusion, problems with vision, speech, or balance;
- chest pain, sudden cough, wheezing, rapid breathing, coughing up blood;
- pain, swelling, warmth, or redness in one or both legs;
- nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- swelling in your hands, ankles, or feet; or
- symptoms of depression (sleep problems, weakness, mood changes).
Less serious side effects may include:
- changes in your menstrual periods;
- weight gain;
- mild headache, drowsiness;
- mild stomach pain;
- hot flashes;
- joint pain;
- breast tenderness;
- feeling tired or irritable;
- decreased sex drive; or
- skin changes or a hard lump where the injection was given.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Depo-Provera (medroxyprogesterone) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about medroxyprogesterone (Depo-Provera)?
Medroxyprogesterone can cause birth defects. Do not use if this medication if you are pregnant. Tell your doctor right away if you become pregnant during treatment. Also tell your doctor if you plan to become pregnant soon after you stop using medroxyprogesterone.
You should not use this medication if you are allergic to medroxyprogesterone, or if you have unusual vaginal bleeding, liver disease, or a history of breast cancer, heart attack, stroke, or blood clot.
Medroxyprogesterone may cause bone loss (osteoporosis) especially when used over long periods of time. Bone loss may not be reversible. Do not use this medication for longer than 2 years. Talk with your doctor about your specific risk of bone loss.
Medroxyprogesterone will not protect you from sexually transmitted diseases--including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.
Additional Depo-Provera Information
- Depo-Provera Drug Interactions Center: medroxyprogesterone im
- Depo-Provera Side Effects Center
- Depo-Provera Overview including Precautions
- Depo-Provera FDA Approved Prescribing Information including Dosage
Depo Provera - User Reviews
Depo Provera User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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