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Brand Names: Andro LA 200, Delatestryl, Depandro 100, Depo-Testosterone, Testosterone Cypionate, Testosterone Enanthate

Generic Name: testosterone injection (Pronunciation: tes TOS ter one)

• What is testosterone injection (Depo-Testosterone)?
• What are the possible side effects of testosterone injection?
• What is the most important information I should know about testosterone injection?
• What should I discuss with my healthcare provider before receiving testosterone injection?
• How is testosterone injection given?
• What happens if I miss a dose?
• What happens if I overdose?
• What should I avoid while receiving testosterone injection?
• What other drugs will affect testosterone injection?
• Where can I get more information?

What is testosterone injection (Depo-Testosterone)?

Testosterone is a naturally occurring sex hormone that is produced in a man's testicles. Small amounts of testosterone are also produced in a woman's ovaries and adrenal system.

Testosterone injection is used in men and boys to treat conditions caused by a lack of this hormone, such as delayed puberty, impotence, or other hormonal imbalances. Testosterone injection is also used in women to treat breast cancer that has spread to other parts of the body.

Testosterone injection may also be used for other purposes not listed in this medication guide.

What are the possible side effects of testosterone injection?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

• swelling, rapid weight gain;
• increased or ongoing erection of the penis;
• bone pain, increased thirst, memory problems, restless feeling, confusion, nausea, loss of appetite, increased urination, weakness, muscle twitching; or
• nausea, vomiting, stomach pain, loss of appetite, and jaundice (yellowing of the skin or eyes).

Women receiving testosterone injection may develop male characteristics, which could be irreversible if testosterone treatment is continued. Call your doctor as soon as possible if you notice any of these signs of excess testosterone:

• acne;
• changes in your menstrual periods;
• male-pattern hair growth (such as on the chin or chest);
• male pattern baldness;
• enlarged clitoris; or
• increase or decrease in sex drive.

Less serious side effects may include:

• breast swelling in men;
• headache, anxiety, depressed mood;
• numbness or tingly feeling; or
• pain or swelling where the medicine was injected.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about testosterone injection?

This medication can cause birth defects in an unborn baby if it is used by a woman during pregnancy. Do not receive testosterone injection if you are pregnant. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.

Do not receive this medication if you have prostate cancer, male breast cancer, if you are pregnant, or if you have ever had an allergic reaction to a hormone treatment.

Before receiving testosterone injection, tell your doctor if you have benign prostatic hypertrophy (BPH), a bleeding or blood clotting disorder, high cholesterol, any type of cancer, liver or kidney disease, or heart disease, coronary artery disease, or a history of heart attack.