The following adverse reactions in the male have occurred with some androgens:
Hematologic: Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy, and polycythemia.
Allergic: Hypersensitivity, including skin manifestations and anaphylactoid reactions.
Drug Abuse And Dependence
Controlled Substance Class: Testosterone is a controlled substance under the Anabolic Steroids Control Act, and DEPO-Testosterone (testosterone cypionate injection) Injection has been assigned to Schedule III.
Read the Depo-Testosterone (testosterone cypionate injection) Side Effects Center for a complete guide to possible side effects »
Androgens may increase sensitivity to oral anticoagulants. Dosage of the anticoagulant may require reduction in order to maintain satisfactory therapeutic hypoprothrombinemia.
Concurrent administration of oxyphenbutazone and androgens may result in elevated serum levels of oxyphenbutazone.
In diabetic patients, the metabolic effects of androgens may decrease blood glucose and, therefore, insulin requirements.
Drug/Laboratory test Interferences
Androgens may decrease levels of thyroxine-binding globulin, resulting in decreased total T4 serum levels and increased resin uptake of T3 and T4. Free thyroid hormone levels remain unchanged, however, and there is no clinical evidence of thyroid dysfunction.
Last reviewed on RxList: 8/25/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional Depo-Testosterone Information
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