Depo-Testosterone Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Depo-Testosterone (testosterone cypionate) Injection is a naturally occurring male sex hormone used in men and boys to treat conditions caused by a lack of this hormone, such as delayed puberty, impotence, or other hormonal imbalances. It is also used in women to treat breast cancer that has spread to other parts of the body. Depo-Testosterone is available in generic form. Common side effects of Depo-Testosterone include nausea, vomiting, headache, anxiety, depression, skin color changes, increased/decreased sexual interest, oily skin, hair loss, breast swelling in men, numbness or tingly feeling, and acne. Pain, swelling, and redness at the injection site may also occur.
The dosage for Depo-Testosterone Injection varies depending on the age, sex, and diagnosis of the individual. Dosage is adjusted according to the patient's response. Depo -Testosterone may interact with blood thinners, insulin or oral diabetes medication, or steroids. Tell your doctor all medications you use. Depo -Testosterone must not be used during pregnancy. It may harm a fetus. Consult your doctor to discuss birth control. Women using this medication should use 2 forms of birth control (i.e., condoms and birth control pills) while using this medication. It is unknown if this drug passes into breast milk. It may affect milk production and it may harm a nursing infant. Breast-feeding while using this drug is not recommended.
Our Depo -Testosterone (testosterone cypionate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Depo-Testosterone in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- swelling, rapid weight gain;
- increased or ongoing erection of the penis;
- bone pain, increased thirst, memory problems, restless feeling, confusion, nausea, loss of appetite, increased urination, weakness, muscle twitching; or
- nausea, vomiting, stomach pain, loss of appetite, and jaundice (yellowing of the skin or eyes).
Women receiving testosterone injection may develop male characteristics, which could be irreversible if testosterone treatment is continued. Call your doctor as soon as possible if you notice any of these signs of excess testosterone:
- changes in your menstrual periods;
- male-pattern hair growth (such as on the chin or chest);
- male pattern baldness;
- enlarged clitoris; or
- increase or decrease in sex drive.
Less serious side effects may include:
- breast swelling in men;
- headache, anxiety, depressed mood;
- numbness or tingly feeling; or
- pain or swelling where the medicine was injected.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Depo-Testosterone (Testosterone Cypionate Injection)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Depo-Testosterone FDA Prescribing Information: Side Effects
The following adverse reactions in the male have occurred with some androgens:
Hematologic: Suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapy, and polycythemia.
Allergic: Hypersensitivity, including skin manifestations and anaphylactoid reactions.
Drug Abuse And Dependence
Controlled Substance Class: Testosterone is a controlled substance under the Anabolic Steroids Control Act, and DEPO-Testosterone (testosterone cypionate injection) Injection has been assigned to Schedule III.
Read the entire FDA prescribing information for Depo-Testosterone (Testosterone Cypionate Injection)
Additional Depo-Testosterone Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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