"Scientists at the National Institutes of Health report they have discovered in mouse studies that a small molecule released in the spinal cord triggers a process that is later experienced in the brain as the sensation of itch.
Desonate Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Desonate (desonide) Gel is a topical (on the skin) corticosteroid used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. Common side effects include mild skin itching, redness, burning, or peeling; dryness or scaly skin; thinning or softening of your skin; skin rash or irritation around your mouth; swollen hair follicles; changes in color of treated skin; blisters, pimples, or crusting of treated skin, or stretch marks.
Apply a thin layer dose of Desonate to the affected areas two times daily and rub in gently. Discontinue use when control is achieved. Treatment beyond 4 consecutive weeks is not recommended. Desonate may interact with other drugs. Tell your doctor all medications and supplements you use. Desonate may be harmful to a fetus. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is unknown if Desonate topical passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.
Our Desonate (desonide) Gel Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Desonate in Detail - Patient Information: Side Effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing desonide topical through your skin, such as:
- blurred vision, or seeing halos around lights;
- mood changes;
- sleep problems (insomnia);
- weight gain, puffiness in your face; or
- muscle weakness, feeling tired.
Less serious side effects may include:
- mild skin itching, redness, burning, or peeling;
- dryness or scaly skin;
- thinning or softening of your skin;
- skin rash or irritation around your mouth;
- swollen hair follicles;
- changes in color of treated skin;
- blisters, pimples, or crusting of treated skin; or
- stretch marks.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Desonate (Desonide Gel) »
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Desonate FDA Prescribing Information: Side Effects
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
In controlled clinical studies of 425 Desonate (desonide gel) -treated subjects and 157 Vehicle-treated subjects, adverse events occurred at the application site in 3% of subjects treated with Desonate (desonide gel) and the incidence rate was not higher compared with vehicle-treated subjects. The most common local adverse events in Desonate (desonide gel) treated subjects were application site burning in 1% (4/425) and rash in 1% (3/425) followed by application site pruritus in < 1% (2/425).
Adverse events that resulted in premature discontinuation of study drug in Desonate (desonide gel) treated subjects were telangiectasia and worsening of atopic dermatitis in one subject each. Additional adverse events observed during clinical trials for patients treated with Desonate (desonide gel) included headache in 2% (8/425) compared with 1% (2/157) in those treated with vehicle.
The following additional local adverse reactions have been reported infrequently with topical corticosteroids. They may occur more frequently with the use of occlusive dressings, especially with higher potency corticosteroids. These reactions are listed in an approximate decreasing order of occurrence: folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, secondary infection, skin atrophy, striae, and miliaria.
Read the entire FDA prescribing information for Desonate (Desonide Gel) »
Additional Desonate Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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