"The beta-blocker propranolol, especially in oral form, more effectively reduces the size and volume of infantile hemangiomas than placebo, observation, and other treatments such as corticosteroids, according to a meta-analysis published online Ja"...
(desonide) Cream 0.05%, Ointment 0.05% and Lotion 0.05%
For Dermatologic Use Only -
Not for Ophthalmic Use -
DesOwen® (desonide cream, ointment and lotion) Cream 0.05%, Ointment 0.05%, and Lotion 0.05% contain desonide (Pregna-1,4-diene-3,20-dione,11,21-dihydroxy- 16,17-[(1-methylethylidene)bis(oxy)]-,(11 β ,16 α )- a synthetic nonfluorinated corticosteroid for topical dermatologic use. The corticosteroids constitute a class of primarily synthetic steroids used topically as antiinflammatory and anti-pruritic agents.
Chemically, desonide is C24H32O6. It has the following structural formula:
Desonide has the molecular weight of 416.51. It is a white to off white odorless powder which is soluble in methanol and practically insoluble in water.
Each gram of DesOwen® (desonide cream, ointment and lotion) Cream contains 0.5 mg of desonide in a base of citric acid, emulsifying wax, isopropyl palmitate, polysorbate 60, potassium sorbate, propyl gallate, propylene glycol, purified water, sodium hydroxide, sorbic acid, stearic acid, and synthetic beeswax.
Each gram of DesOwen® (desonide cream, ointment and lotion) Ointment contains 0.5 mg of desonide in a base of mineral oil and polyethylene.
Each gram of DesOwen® (desonide cream, ointment and lotion) Lotion contains 0.5 mg of desonide in a base of cetyl alcohol, edetate sodium, glyceryl stearate SE, light mineral oil, methylparaben, propylene glycol, propylparaben, purified water, sodium lauryl sulfate, sorbitan monostearate, and stearyl alcohol. May contain citric acid and/or sodium hydroxide for pH adjustment.
What are the possible side effects of desonide topical?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing desonide topical through your skin, such as:
- blurred vision, or seeing halos around lights;
- mood changes;
- sleep problems (insomnia);
- weight gain, puffiness in your face; or
- muscle weakness, feeling tired.
Less serious side effects may...
What are the precautions when taking desonide cream, ointment and lotion (DesOwen)?
Before using desonide, tell your doctor or pharmacist if you are allergic to it; or to other corticosteroids (e.g., hydrocortisone, prednisone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, diabetes, immune system problems, other skin conditions (e.g., rosacea, perioral dermatitis).
Do not use if there is an infection or sore in the area to be treated.
Children may be more sensitive to the effects of too much corticosteroid medication. Consult your doctor for more details.
This medication should be used only...
Last reviewed on RxList: 8/11/2008
This monograph has been modified to include the generic and brand name in many instances.
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