Brand Names: Desyrel, Oleptro

Generic Name: trazodone (Pronunciation: TRAZ oh done)

• What is trazodone (Desyrel)?
• What are the possible side effects of trazodone (Desyrel)?
• What is the most important information I should know about trazodone (Desyrel)?
• What should I discuss with my healthcare provider before taking trazodone (Desyrel)?
• How should I take trazodone (Desyrel)?
• What happens if I miss a dose (Desyrel)?
• What happens if I overdose (Desyrel)?
• What should I avoid while taking trazodone (Desyrel)?
• What other drugs will affect trazodone (Desyrel)?
• Where can I get more information?

What is trazodone (Desyrel)?

Trazodone is an antidepressant medication. It affects chemicals in the brain that may become unbalanced and cause depression

Trazodone is used to treat depression.

Trazodone may also be used for other purposes not listed in this medication guide.

Desyrel 150 mg

rectangular, peach, imprinted with MJ 778, 50 50 50

Trazodone 100 mg-BAR

round, white, imprinted with barr, 555 490

Trazodone 100 mg-MUT

round, white, imprinted with MP 114

Trazodone 100 mg-SID

round, white, imprinted with SL 434

Trazodone 100 mg-TEV

round, white, imprinted with 93 638

Trazodone 100 mg-WAT

round, white, imprinted with 5599, DAN DAN

Trazodone 150 mg-BAR

oval, white, imprinted with barr 732, 50 50 50

Trazodone 150 mg-MUT

round, white, imprinted with 25 25 50 50, MP 168

Trazodone 150 mg-SID

trapezoid, white, imprinted with SL 441, 50 50 50

Trazodone 150 mg-WAT

round, white, imprinted with 2525 5050, MP168

Trazodone 300 mg-BAR

oval, white, imprinted with barr 733, 100 100 100

Trazodone 50 mg-BAR

round, white, imprinted with barr, 555 489

Trazodone 50 mg-MUT

round, white, imprinted with MP 118

Trazodone 50 mg-SID

round, white, imprinted with SL 433

Trazodone 50 mg-TEV

round, white, imprinted with 93 637

Trazodone 50 mg-WAT

round, white, imprinted with 5600, DAN DAN

What are the possible side effects of trazodone (Desyrel)?

Stop taking trazodone and call your doctor at once if you have a penis erection that is painful or lasts 6 hours or longer. This is a medical emergency and could lead to a serious condition that must be corrected with surgery.

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Stop taking trazodone and call your doctor at once if you have a serious side effect such as:

• extreme mood swings, restlessness, or sleep problems;
• dizziness, fainting, fast or pounding heartbeat;
• easy bruising or bleeding;
• agitation, hallucinations, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination;
• very stiff (rigid) muscles, high fever, confusion, fast or uneven heartbeats, tremors, feeling like you might pass out;
• headache, trouble concentrating, memory problems, weakness, loss of appetite, feeling unsteady, seizure, shallow breathing or breathing that stops; or
• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling.

Less serious side effects may be more likely to occur, such as:

• drowsiness;
• mild headache;
• constipation; or
• blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Desyrel (trazodone hydrochloride) Side Effects Center for a complete guide to possible side effects »

What is the most important information I should know about trazodone (Desyrel)?

Before taking trazodone, tell your doctor if you have bipolar disorder (manic depression), heart disease or "Long QT syndrome," liver or kidney disease, a history of drug abuse or suicidal thoughts, or if you have recently had a heart attack.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Trazodone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Stop taking trazodone and call your doctor at once if you have a penis erection that is painful or lasts 6 hours or longer. This is a medical emergency and could lead to a serious condition that must be corrected with surgery.