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There have been no reports of significant overdose of DEXILANT. Multiple doses of DEXILANT 120 mg and a single dose of DEXILANT 300 mg did not result in death or other severe adverse events. However, serious adverse events of hypertension have been reported in association with twice daily doses of DEXILANT 60 mg. Non-serious adverse reactions observed with twice daily doses of DEXILANT 60 mg include hot flashes, contusion, oropharyngeal pain, and weight loss. Dexlansoprazole is not expected to be removed from the circulation by hemodialysis. If an overdose occurs, treatment should be symptomatic and supportive.
DEXILANT is contraindicated in patients with known hypersensitivity to any component of the formulation [see DESCRIPTION]. Hypersensitivity and anaphylaxis have been reported with DEXILANT use. Acute interstitial nephritis has been reported with other proton pump inhibitors (PPIs), including lansoprazole [see ADVERSE REACTIONS].This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 1/8/2015
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