"Today, the U.S. Food and Drug Administration approved Topamax (topiramate) for prevention (prophylaxis) of migraine headaches in adolescents ages 12 to 17. This is the first FDA approval of a drug for migraine prevention in this age group. The me"...
D. H. E. 45
D. H. E. 45 Patient Information including If I Miss a Dose
In this Article
- What is dihydroergotamine injection (D. H. E. 45)?
- What are the possible side effects of dihydroergotamine injection (D. H. E. 45)?
- What is the most important information I should know about dihydroergotamine injection (D. H. E. 45)?
- What should I discuss with my healthcare provider before using dihydroergotamine injection (D. H. E. 45)?
- How should I use dihydroergotamine injection (D. H. E. 45)?
- What happens if I miss a dose (D. H. E. 45)?
- What happens if I overdose (D. H. E. 45)?
- What should I avoid while using dihydroergotamine injection (D. H. E. 45)?
- What other drugs will affect dihydroergotamine injection (D. H. E. 45)?
- Where can I get more information?
What happens if I miss a dose (D. H. E. 45)?
Since dihydroergotamine is used on an as-needed basis, you are not likely to miss a dose. Do not use more than 3 injections of dihydroergotamine per day or more than 6 injections per week.
What happens if I overdose (D. H. E. 45)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of dihydroergotamine can be fatal. Overdose symptoms may include some of the serious side effects listed in this medication guide.
What should I avoid while using dihydroergotamine injection (D. H. E. 45)?
Do not use dihydroergotamine injection within 24 hours before or after using another migraine headache medicine, including:
- another ergot medicine such as ergotamine (Ergomar, Cafergot, Migergot), dihydroergotamine (Migranal), or methylergonovine (Methergine); or
- almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), sumatriptan (Imitrex), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig).
Grapefruit and grapefruit juice may interact with dihydroergotamine injection and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor.
What other drugs will affect dihydroergotamine injection (D. H. E. 45)?
Many drugs can interact with dihydroergotamine. Below is just a partial list. Tell your doctor if you are using:
- zileuton (Zyflo);
- nicotine (Nicoderm, Nicorette);
- cold or allergy medications, diet pills, stimulants, or medication to treat ADHD (such as Ritalin or Adderall);
- an antidepressant such fluoxetine (Prozac), sertraline (Zoloft), and others;
- fluconazole (Diflucan) or other antifungal medication; or
- heart or blood pressure medication such as atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal, InnoPran), and others.
This list is not complete and other drugs may interact with dihydroergotamine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about dihydroergotamine injection.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Additional D. H. E. 45 Information
- D. H. E. 45 Drug Interactions Center: dihydroergotamine inj
- D. H. E. 45 Side Effects Center
- D. H. E. 45 Overview including Precautions
- D. H. E. 45 FDA Approved Prescribing Information including Dosage
D. H. E. 45 - User Reviews
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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