Diamox Sequels (Acetazolamide XR) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Diamox Sequels

Seizure (Epilepsy) »

Introduction

Few experiences match the drama of a convulsive seizure. A person having a severe seizure may cry out, fall to the floor unconscious, twitch or move uncontrollably, drool, or even lose bladder control. Within minutes, the attack is over, and the person regains consciousness but is exhausted and dazed. This is the image most people have when they hear the word epilepsy. However, this type of seizure -- a generalized tonic-clonic seizure -- is only one kind of epilepsy. There are many other kinds, each with a different set of symptoms.

Epilepsy was one of the first brain disorders to be described. It was mentioned in ancient Babylon more than 3,000 years ago. The strange behavior caused by some seizures has contributed through the ages to many superstitions and prejudices. The word epilepsy is derived from the Greek word for "attack." People once thought that those with epilepsy were being visited by demons or gods. However, in 400 B.C., the early...

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DIAMOX® SEQUELS®
(acetazolamide) Extended-Release Capsules

DRUG DESCRIPTION

DIAMOX SEQUELS (Acetazolamide Extended-Release Capsules) are an inhibitor of the enzyme carbonic anhydrase.

DIAMOX is a white to faintly yellowish white crystalline, odorless powder, weakly acidic, very slightly soluble in water and slightly soluble in alcohol. The chemical name for DIAMOX is N-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide and has the following chemical structure:

DIAMOX SEQUELS (Acetazolamide) structural formula illustration

MW 222.24........C₄H₆N₄0₃S₂

DIAMOX SEQUELS (acetazolamide xr) are extended-release capsules, for oral administration, each containing 500 mg of acetazolamide and the following inactive ingredients:

Microcrystalline cellulose, sodium lauryl sulfate and talc.

The ingredients in the capsule shell are D&C red no. 28, D&C yellow no. 10, FD&C red no. 40, gelatin and titanium dioxide.

The ingredients in the imprinting ink are D&C yellow no. 10 aluminum lake, FD&C blue no. 1 aluminum lake, FD&C blue no. 2 aluminum lake, FD&C red no. 40 aluminum lake, pharmaceutical glaze, propylene glycol and synthetic iron oxide.

What are the possible side effects of acetazolamide (Diamox, Diamox Sequels)?

If you experience any of the following serious side effects, stop taking acetazolamide and seek emergency medical attention:

an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
a sore throat or a fever;
unusual bleeding or bruising;
side or groin pain;
tingling or tremors in your hands or feet; or
a rash.

Other, less serious side effects may be more likely to occur. Continue to...

Read All Potential Side Effects and See Pictures of Diamox Sequels »

What are the precautions when taking acetazolamide xr (Diamox Sequels)?

Before taking acetazolamide, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: adrenal gland problems (e.g., Addison's disease), low blood levels of sodium or potassium, severe kidney disease, severe liver disease (e.g., cirrhosis), certain metabolic problems (e.g., hyperchloremic acidosis).

Before using this medication, tell your doctor or pharmacist your medical history, especially of: breathing problems (e.g., emphysema, chronic...

Read All Potential Precautions of Diamox Sequels »

Last reviewed on RxList: 1/7/2009
This monograph has been modified to include the generic and brand name in many instances.