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In this Article

• What is diazepam rectal (Diastat)?
• What are the possible side effects of diazepam rectal (Diastat)?
• What is the most important information I should know about diazepam rectal (Diastat)?
• What should I discuss with my healthcare provider before using diazepam rectal (Diastat)?
• How should I use diazepam rectal (Diastat)?
• What happens if I miss a dose (Diastat)?
• What happens if I overdose (Diastat)?
• What should I avoid while using diazepam rectal (Diastat)?
• What other drugs will affect diazepam rectal (Diastat)?
• Where can I get more information?

What happens if I miss a dose (Diastat)?

Use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose (Diastat)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, fainting, or coma.

What should I avoid while using diazepam rectal (Diastat)?

Do not drink alcohol while using diazepam rectal. This medication can increase the effects of alcohol.

Diazepam rectal can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, or muscle relaxers). They can increase some of the side effects of diazepam rectal.

What other drugs will affect diazepam rectal (Diastat)?

Before using diazepam rectal, tell your doctor if you are using any of the following drugs:

• cimetidine (Tagamet);
• valproate (Depakene);
• a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Luminal, Solfoton);
• an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate);
• medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), mesoridazine (Serentil), pimozide (Orap), or thioridazine (Mellaril);
• narcotic medications such as butorphanol (Stadol), codeine, hydrocodone (Lortab, Vicodin), levorphanol (Levo-Dromoran), meperidine (Demerol), methadone (Dolophine, Methadose), morphine (Kadian, MS Contin, Oramorph), naloxone (Narcan), oxycodone (OxyContin), propoxyphene (Darvon, Darvocet); or
• antidepressants such as amitriptyline (Elavil, Etrafon), amoxapine (Asendin), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Janimine, Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), protriptyline (Vivactil), sertraline (Zoloft), or trimipramine (Surmontil).

This list is not complete and there may be other drugs that can interact with diazepam rectal. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about diazepam rectal.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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