Dibenzyline (Phenoxybenzamine) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Dibenzyline

High Blood Pressure »

High blood pressure facts

High blood pressure (hypertension) is designated as either essential (primary) hypertension or secondary hypertension and is defined as a consistently elevated blood pressure exceeding 140/90 mm Hg.
High blood pressure is called "the silent killer" because it often causes no symptoms for many years, even decades, until it finally damages certain critical organs.
Poorly controlled high blood pressure ultimately can cause damage to blood vessels in the eye, thickening of the heart muscle and heart attacks, hardening of the arteries (arteriosclerosis), kidney failure, and strokes.
Most antihypertensive medications can be used alone or in combination. Some are used only in combination. Some are preferred over others in certain specific medical situations. And some are not to be used (contraindicated) in other situations.
Several classes of antihypertensive medications are available, including ACE i...

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Dibenzyline

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DIBENZYLINE®
(phenoxybenzamine hydrochloride) Capsules, USP
10 mg Adrenergic, Alpha-Receptor- blocking agent

DRUG DESCRIPTION

Each Dibenzyline (phenoxybenzamine) capsule, with red cap and body, is imprinted WPC 001 and 10 mg, and contains 10 mg of Phenoxybenzamine Hydrochloride USP. Inactive ingredients consist of D&C Red No. 33, FD&C Red No. 3, FD&C Yellow No. 6, Gelatin NF, Lactose NF, Sodium Lauryl Sulfate NF and Silicon Dioxide NF.

Dibenzyline (phenoxybenzamine) is N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride:

Dibenzyline (phenoxybenzamine hydrochloride) structural formula illustration

Phenoxybenzamine hydrochloride is a colorless, crystalline powder with a molecular weight of 340.3, which melts between 136° and 141°C. It is soluble in water, alcohol and chloroform; insoluble in ether.

What are the possible side effects of phenoxybenzamine (Dibenzyline)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using phenoxybenzamine and call your doctor at once if you severe dizziness or if you feel like you might pass out.

Less serious side effects may include:

stuffy nose;
mild dizziness or drowsiness;
blurred vision;
trouble having an orgasm;
upset stomach; or
tired...

Read All Potential Side Effects and See Pictures of Dibenzyline »

What are the precautions when taking phenoxybenzamine (Dibenzyline)?

Before taking phenoxybenzamine, tell your doctor or pharmacist if you are allergic to it; or to other alpha blockers (e.g., phentolamine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood vessel disease (e.g., cerebral arteriosclerosis, coronary artery disease), heart disease (e.g., congestive heart failure), kidney disease, lung infections.

Before having surgery, tell your doctor or dentist that you are taking this medication.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires...

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Last reviewed on RxList: 5/14/2008
This monograph has been modified to include the generic and brand name in many instances.