"The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended the marketing of selexipag (Uptravi, Actelion Registration Ltd) for the treatment of adults with pulmonary arterial hypertension (PAH)./"...
(phenoxybenzamine hydrochloride) Capsules, USP
10 mg Adrenergic, Alpha-Receptor- blocking agent
Each Dibenzyline (phenoxybenzamine) capsule, with red cap and body, is imprinted WPC 001 and 10 mg, and contains 10 mg of Phenoxybenzamine Hydrochloride USP. Inactive ingredients consist of D&C Red No. 33, FD&C Red No. 3, FD&C Yellow No. 6, Gelatin NF, Lactose NF, Sodium Lauryl Sulfate NF and Silicon Dioxide NF.
Dibenzyline (phenoxybenzamine) is N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride:
Phenoxybenzamine hydrochloride is a colorless, crystalline powder with a molecular weight of 340.3, which melts between 136° and 141°C. It is soluble in water, alcohol and chloroform; insoluble in ether.
What are the possible side effects of phenoxybenzamine (Dibenzyline)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using phenoxybenzamine and call your doctor at once if you severe dizziness or if you feel like you might pass out.
Less serious side effects may include:
- stuffy nose;
- mild dizziness or drowsiness;
- blurred vision;
- trouble having an orgasm;
- upset stomach; or
- tired feeling.
This is not a complete list of side effects and others may occur....
What are the precautions when taking phenoxybenzamine (Dibenzyline)?
Before taking phenoxybenzamine, tell your doctor or pharmacist if you are allergic to it; or to other alpha blockers (e.g., phentolamine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood vessel disease (e.g., cerebral arteriosclerosis, coronary artery disease), heart disease (e.g., congestive heart failure), kidney disease, lung infections, certain eye problems (cataracts, glaucoma).
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such...
Last reviewed on RxList: 5/14/2008
This monograph has been modified to include the generic and brand name in many instances.
Additional Dibenzyline Information
Dibenzyline - User Reviews
Dibenzyline User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get tips on handling your hypertension.